Bioinspired surfaces with wettability: biomolecule adhesion behaviors.

Surface wettability plays an important role in regulating biomolecule adhesion behaviors. The biomolecule adhesion behaviors of superwettable surfaces have become an important topic as an important part of the interactions between materials and organisms. In addition to general research on the moderate wettability of surfaces, the studies of biomolecule adhesion behaviors extend to extreme wettability ranges such as superhydrophobic, superhydrophilic and slippery surfaces and attract both fundamental and practical interest. In this review, we summarize the recent studies on biomolecule adhesion behaviors on superwettable surfaces, especially superhydrophobic, superhydrophilic and slippery surfaces. The first part will focus on the influence of extreme wettability on cell adhesion behaviors. The second part will concentrate on the adhesion behaviors of biomacromolecules on superwettable surfaces including proteins and nucleic acids. Finally, the influences of wettability on small molecule adhesion behaviors on material surfaces have also been investigated. The mechanism of superwettable surfaces and their influences on biomolecule adhesion behaviors have been studied and highlighted.