Literature DB >> 31991282

Post-trauma anhedonia is associated with increased substance use in a recently-traumatized population.

Negar Fani1, Jahnvi Jain2, Lauren A Hudak3, Barbara O Rothbaum2, Kerry J Ressler4, Vasiliki Michopoulos5.   

Abstract

Recreational substance use (SU) can emerge or worsen in the aftermath of psychological trauma. Anhedonia is one reason for this problematic SU. Symptoms of posttraumatic stress disorder (PTSD) that represent anhedonia (post-trauma anhedonia; PTA) have been consistently linked to SU disorders. However, no prospective studies have examined whether changes in PTA over time are associated with problematic SU in recently-traumatized people, which was the goal of this study. 165 men and women were recruited as part of a prospective PTSD study in the emergency department of a Level 1 trauma center. Clinical assessments of PTSD and SU were administered at three and six months post-trauma. Compared to participants with minimal SU at six months post-trauma, high substance users at six months post-trauma showed significant increases in PTA during the three to six month time period. This relationship was significant even after accounting for variance associated with other factors, including PTSD symptoms such as re-experiencing and hyperarousal. Participants who demonstrated increases in SU during this time also showed significant increases in PTA, unlike those who demonstrated consistently minimal/no SU during this time. These findings indicate that PTA may be a mechanism through which SU problems emerge in recently-traumatized individuals.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Anhedonia; Emergency department; PTSD; Substance use; Trauma

Year:  2020        PMID: 31991282      PMCID: PMC7544530          DOI: 10.1016/j.psychres.2020.112777

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN: 0165-1781            Impact factor:   3.222


  63 in total

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