| Literature DB >> 3199072 |
T Kiyohara1, K Taniguchi, S Kubota, S Koga, T Sakuragi, Y Saitoh.
Abstract
Natural cell-mediated cytotoxicity against NK-resistant target tumor cells was found in the peripheral blood of tumor-bearing patients approximately 1 mo after combined chemotherapy. The recognition specificity of these effector cells was broad and had no restriction. From the experiments of negative selection with mAbs and complements, these newly developed killer cells after chemotherapy were thought to be LAK-like cells. Contribution of these LAK-like cells to the mechanism of action of anticancer drugs remains to be clarified.Entities:
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Year: 1988 PMID： 3199072 PMCID： PMC2189131 DOI： 10.1084/jem.168.6.2355
Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307