Literature DB >> 31990000

Biotinylated photoactive Pt(iv) anticancer complexes.

Huayun Shi1, Cinzia Imberti, Huaiyi Huang, Ian Hands-Portman, Peter J Sadler.   

Abstract

Novel biotinylated diazido-Pt(iv) complexes exhibit high visible light photocytotoxicity while being stable in the dark. Photocytotoxicity and cellular accumulation of all-trans-[Pt(py)2(N3)2(biotin)(OH)] (2a) were enhanced significantly when bound to avidin; irradiation induced dramatic cellular morphological changes in human ovarian cancer cells treated with 2a.

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Year:  2020        PMID： 31990000     DOI： 10.1039/c9cc07845b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Synthesis and anticancer activity of two highly water-soluble and ionic Pt(iv) complexes as prodrugs for Pt(ii) anticancer drugs.

Authors:  Anli Gao; Yaxi Wu; Juan Yu; Hongyu Gong; Jing Jiang; Caihong Yang; Weiping Liu; Chen Qing
Journal:  RSC Med Chem       Date:  2022-03-18

2.  A theoretical study on the on-off phosphorescence of novel Pt(ii)/Pt(iv)-bisphenylpyridinylmethane complexes.

Authors:  Guoxun Zhu; Zhenping Chen; Huacan Song; Ao You; Zhengquan Li
Journal:  RSC Adv       Date:  2022-06-22       Impact factor: 4.036

Review 3.  Ligand Evolution in the Photoactivatable Platinum(IV) Anticancer Prodrugs.

Authors:  Jingjing Huang; Weize Ding; Xingfan Zhu; Bingbing Li; Fangang Zeng; Kui Wu; Xiaoqin Wu; Fuyi Wang
Journal:  Front Chem       Date:  2022-06-09       Impact factor: 5.545

4.  Axial functionalisation of photoactive diazido platinum(iv) anticancer complexes.

Authors:  Huayun Shi; Cinzia Imberti; Guy J Clarkson; Peter J Sadler
Journal:  Inorg Chem Front       Date:  2020-08-26       Impact factor: 6.569

5.  Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes.

Authors:  Elizabeth M Bolitho; Carlos Sanchez-Cano; Huayun Shi; Paul D Quinn; Maria Harkiolaki; Cinzia Imberti; Peter J Sadler
Journal:  J Am Chem Soc       Date:  2021-11-22       Impact factor: 15.419

6.  Synthesis and In Vitro Studies of Photoactivatable Semisquaraine-type Pt(II) Complexes.

Authors:  Kevin Morales; Sergi Rodríguez-Calado; Jordi Hernando; Julia Lorenzo; Antonio Rodríguez-Diéguez; Carlos Jaime; Pau Nolis; Mercè Capdevila; Òscar Palacios; Marta Figueredo; Pau Bayón
Journal:  Inorg Chem       Date:  2022-05-06       Impact factor: 5.436

7.  Ferroptosis promotes sonodynamic therapy: a platinum(ii)-indocyanine sonosensitizer.

Authors:  Yidan Lai; Nong Lu; Ai Ouyang; Qianling Zhang; Pingyu Zhang
Journal:  Chem Sci       Date:  2022-08-05       Impact factor: 9.969

8.  Facile protein conjugation of platinum for light-activated cytotoxic payload release.

Authors:  Cinzia Imberti; Frederik Lermyte; Emily P Friar; Peter B O'Connor; Peter J Sadler
Journal:  Chem Commun (Camb)       Date:  2021-08-03       Impact factor: 6.222
  8 in total

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