Eden Towers1, Adriane Morrison-Taylor1, Jennifer Demar1, Andrew Klansky1, Kasie Craig1, Hans Christian Haverkamp2. 1. Department of Environmental and Health Sciences, Northern Vermont University-Johnson, 337 College Hill Road, Johnson, VT, 05405, USA. 2. Department of Nutrition and Exercise Physiology, Elson S. Floyd College of Medicine, Washington State University, PO Box 1495, Spokane, WA, 99210-1495, USA. hans.haverkamp@wsu.edu.
Abstract
PURPOSE:Hyperpnea training has been used as a method for both improving exercise performance in healthy persons and improving ventilatory capacity in patients with pulmonary disease. However, voluntary hyperpnea causes acute declines in pulmonary function, but the effects of repeated days of hyperpnea on airway function are not known. The purpose of this study was to determine the effects of repeated normocapnic hyperpnea on daily and post-hyperpnea pulmonary function in healthy adults. METHODS:Ten healthy adults (21 years; 170 cm; 66 kg) completed tenhyperpnea training sessions within 17-days (TR). Training sessions consisted of 20-minutes of normocapnic hyperpnea with gradually increased minute ventilation over the 10 days. Spirometry was assessed at baseline and serially following hyperpnea during each experimental day. A control group (24 years; 171 cm; 66 kg) completed 10 days of spirometry with no hyperpnea training (CON). RESULTS: In both CON and TR subjects, baseline pulmonary function was unchanged during the 10 days. In TR subjects, pulmonary function was decreased at 5 mins after hyperpnea but thereafter increased to pre-hyperpnea values by 30 mins. Furthermore, these changes in pulmonary function were consistent during the 10 training days. In TR subjects, maximal voluntary ventilation decreased by 10.4 ± 8.9% (168-150 L min-1) over the 10 days (P < 0.05), whereas it was unchanged in CON subjects. CONCLUSIONS: These findings demonstrate that voluntary hyperpnea acutely decreases airway function in healthy subjects. However, there does not appear to be a cumulative effect of repeated hyperpnea, as daily pulmonary function was unchanged.
RCT Entities:
PURPOSE: Hyperpnea training has been used as a method for both improving exercise performance in healthy persons and improving ventilatory capacity in patients with pulmonary disease. However, voluntary hyperpnea causes acute declines in pulmonary function, but the effects of repeated days of hyperpnea on airway function are not known. The purpose of this study was to determine the effects of repeated normocapnic hyperpnea on daily and post-hyperpnea pulmonary function in healthy adults. METHODS: Ten healthy adults (21 years; 170 cm; 66 kg) completed ten hyperpnea training sessions within 17-days (TR). Training sessions consisted of 20-minutes of normocapnic hyperpnea with gradually increased minute ventilation over the 10 days. Spirometry was assessed at baseline and serially following hyperpnea during each experimental day. A control group (24 years; 171 cm; 66 kg) completed 10 days of spirometry with no hyperpnea training (CON). RESULTS: In both CON and TR subjects, baseline pulmonary function was unchanged during the 10 days. In TR subjects, pulmonary function was decreased at 5 mins after hyperpnea but thereafter increased to pre-hyperpnea values by 30 mins. Furthermore, these changes in pulmonary function were consistent during the 10 training days. In TR subjects, maximal voluntary ventilation decreased by 10.4 ± 8.9% (168-150 L min-1) over the 10 days (P < 0.05), whereas it was unchanged in CON subjects. CONCLUSIONS: These findings demonstrate that voluntary hyperpnea acutely decreases airway function in healthy subjects. However, there does not appear to be a cumulative effect of repeated hyperpnea, as daily pulmonary function was unchanged.
Authors: Samuel Verges; Oliver Lenherr; Andrea C Haner; Christian Schulz; Christina M Spengler Journal: Am J Physiol Regul Integr Comp Physiol Date: 2006-10-26 Impact factor: 3.619
Authors: Samuel Verges; Andrea S Renggli; Dominic A Notter; Christina M Spengler Journal: Respir Physiol Neurobiol Date: 2009-09-15 Impact factor: 1.931