Pamela Di Giovanni1, Piera Scampoli2, Francesca Meo3, Fabrizio Cedrone3, Michela D'Addezio3, Giuseppe Di Martino3, Alessandra Valente3, Ferdinando Romano4, Tommaso Staniscia5. 1. Department of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy. 2. School of Hygiene and Preventive Medicine, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy. Electronic address: piera.scampoli@gmail.com. 3. School of Hygiene and Preventive Medicine, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy. 4. Department of Public Health and Infectious Disease, "La Sapienza" University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy. 5. Department of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy.
Abstract
BACKGROUND: Diabetes-related lower extremity amputations (LEAs) are a major public health issue. The aim of the study was to evaluate trends by gender and predictors of LEAs in an Italian region. METHODS: Data were collected from hospital discharge records between 2006 and 2015. Gender- and age-adjusted standardised hospitalisation rates for major and minor amputations were calculated. Poisson regression model was performed to estimate trends in LEAs. RESULTS: Hospitalisation rates decreased for minor amputations both among males (-30.0%) and females (-5.3%), while the major amputation rates decreased only for males (-44.7%). Males were at higher risk of undergoing major (IRR 1.41, 95%CI 1.19-1.67) and minor (IRR 1.62, 95%CI 1.45-1.82) amputations. Peripheral vascular disease was the leading predictor of major and minor amputations. CONCLUSION: A significant reduction of LEAs was observed only for males. Identifying their predictable factors may help caregivers to provide higher standards of diabetes care.
BACKGROUND:Diabetes-related lower extremity amputations (LEAs) are a major public health issue. The aim of the study was to evaluate trends by gender and predictors of LEAs in an Italian region. METHODS: Data were collected from hospital discharge records between 2006 and 2015. Gender- and age-adjusted standardised hospitalisation rates for major and minor amputations were calculated. Poisson regression model was performed to estimate trends in LEAs. RESULTS: Hospitalisation rates decreased for minor amputations both among males (-30.0%) and females (-5.3%), while the major amputation rates decreased only for males (-44.7%). Males were at higher risk of undergoing major (IRR 1.41, 95%CI 1.19-1.67) and minor (IRR 1.62, 95%CI 1.45-1.82) amputations. Peripheral vascular disease was the leading predictor of major and minor amputations. CONCLUSION: A significant reduction of LEAs was observed only for males. Identifying their predictable factors may help caregivers to provide higher standards of diabetes care.
Authors: Mozania Reis de Matos; Daniele Pereira Santos-Bezerra; Cristiane das Graças Dias Cavalcante; Jacira Xavier de Carvalho; Juliana Leite; Jose Antonio Januario Neves; Sharon Nina Admoni; Marisa Passarelli; Maria Candida Parisi; Maria Lucia Correa-Giannella Journal: Int J Environ Res Public Health Date: 2020-05-06 Impact factor: 3.390