Tomohiko Hasegawa1, Hiroki Ushirozako2, Yu Yamato3, Daisuke Togawa4, Go Yoshida2, Sho Kobayashi5, Tatsuya Yasuda2, Tomohiro Banno2, Hideyuki Arima2, Shin Oe3, Tomohiro Yamada2, Koichiro Ide2, Yuh Watanabe2, Yukihiro Matsuyama2. 1. Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashiku, Hamamatsu, Shizuoka, 431-3192, Japan. hasetomo@hama-med.ac.jp. 2. Department of Orthopedic Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashiku, Hamamatsu, Shizuoka, 431-3192, Japan. 3. Department of Orthopedic Surgery and Division of Geriatric Musculoskeletal Health, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan. 4. Department of Orthopaedic Surgery, Kindai University Nara Hospital, Ikoma, Nara, Japan. 5. Department of Orthopaedic Surgery, Hamamatsu Medical Center, Hamamatsu, Shizuoka, Japan.
Abstract
PURPOSE: Gastroesophageal reflux disease (GERD) is reported as one of the symptoms of adult spinal deformity (ASD). Little is known about the mid- to long-term improvement in GERD symptoms after ASD surgery. Therefore, this retrospective study from prospectively collected database aimed to investigate GERD symptoms in patients for a minimum of 2 years after ASD corrective surgery. METHODS: Records from 230 patients (mean age: 64 years) who underwent ASD surgery were examined using the frequency scale for the symptoms of GERD (FSSG) questionnaires for the diagnosis of GERD. FSSG scores and radiographic parameters were investigated preoperatively and postoperatively at 6 months and 1, 2, and 5 years. RESULTS: In total, 90 (39%) patients were preoperatively diagnosed with GERD defined by FSSG score ≥ 8 points. Radiographic results showed that the corrective surgeries improved local and global alignments. In the GERD patients, preoperative FSSG scores (16.1 ± 7.3 points) significantly improved to 7.7 ± 7.4 points within 6 months postoperatively (p < 0.001), and postoperative FSSG scores maintained at 1 year (9.9 ± 8.2 points, p = 0.061), 2 years (9.7 ± 8.2 points, p = 0.086), and 5 years (9.4 ± 8.0 points, p = 0.177). Among the GERD group, 62 patients (69%; improvement cases) showed improvement in GERD symptoms defined by FSSG score < 8 points within 6 months postoperatively. CONCLUSIONS: Among ASD patients, 39% were diagnosed with GERD. In 69% of these patients, GERD symptoms improved within 6 months of corrective surgery and maintained up to 5 years postoperatively. These slides can be retrieved under Electronic Supplementary Material.
PURPOSE:Gastroesophageal reflux disease (GERD) is reported as one of the symptoms of adult spinal deformity (ASD). Little is known about the mid- to long-term improvement in GERD symptoms after ASD surgery. Therefore, this retrospective study from prospectively collected database aimed to investigate GERD symptoms in patients for a minimum of 2 years after ASD corrective surgery. METHODS: Records from 230 patients (mean age: 64 years) who underwent ASD surgery were examined using the frequency scale for the symptoms of GERD (FSSG) questionnaires for the diagnosis of GERD. FSSG scores and radiographic parameters were investigated preoperatively and postoperatively at 6 months and 1, 2, and 5 years. RESULTS: In total, 90 (39%) patients were preoperatively diagnosed with GERD defined by FSSG score ≥ 8 points. Radiographic results showed that the corrective surgeries improved local and global alignments. In the GERDpatients, preoperative FSSG scores (16.1 ± 7.3 points) significantly improved to 7.7 ± 7.4 points within 6 months postoperatively (p < 0.001), and postoperative FSSG scores maintained at 1 year (9.9 ± 8.2 points, p = 0.061), 2 years (9.7 ± 8.2 points, p = 0.086), and 5 years (9.4 ± 8.0 points, p = 0.177). Among the GERD group, 62 patients (69%; improvement cases) showed improvement in GERD symptoms defined by FSSG score < 8 points within 6 months postoperatively. CONCLUSIONS: Among ASDpatients, 39% were diagnosed with GERD. In 69% of these patients, GERD symptoms improved within 6 months of corrective surgery and maintained up to 5 years postoperatively. These slides can be retrieved under Electronic Supplementary Material.
Authors: N Furukawa; R Iwakiri; T Koyama; K Okamoto; T Yoshida; Y Kashiwagi; T Ohyama; T Noda; H Sakata; K Fujimoto Journal: J Gastroenterol Date: 1999-08 Impact factor: 7.527
Authors: Justin S Smith; Christopher I Shaffrey; Virginie Lafage; Frank Schwab; Justin K Scheer; Themistocles Protopsaltis; Eric Klineberg; Munish Gupta; Richard Hostin; Kai-Ming G Fu; Gregory M Mundis; Han Jo Kim; Vedat Deviren; Alex Soroceanu; Robert A Hart; Douglas C Burton; Shay Bess; Christopher P Ames Journal: J Neurosurg Spine Date: 2015-06-05