Literature DB >> 31980296

New and Emerging Medications for Treatment of Pediatric Epilepsy.

M Scott Perry1.   

Abstract

BACKGROUND: Multiple medications have recently been approved or are nearing US Food and Drug Administration approval for treatment of pediatric epilepsy, while a number of other compounds are in development. Many of these therapies are seeking indications in rare epilepsy syndromes and present novel mechanisms of action for the treatment of epilepsy.
METHODS: Data related to drugs in development or under study were accessed following literature search via PubMed or author knowledge of publically available data.
RESULTS: Several new compounds are recently approved or under study for epilepsy in children.
CONCLUSIONS: The following is a brief overview of the new and emerging medications for the treatment of pediatric epilepsy.
Copyright © 2019 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Antisense oligonucleotide; Cannabidiol; Fenfluramine; Ganaxolone; OV935

Mesh:

Substances:

Year:  2019        PMID: 31980296     DOI: 10.1016/j.pediatrneurol.2019.11.008

Source DB:  PubMed          Journal:  Pediatr Neurol        ISSN: 0887-8994            Impact factor:   3.372


  4 in total

1.  On disturbance rejection control of the epileptiform spikes.

Authors:  Wei Wei; Zhiyuan Zhang; Nan Chen; Min Zuo; Tao Yu
Journal:  Cogn Neurodyn       Date:  2021-09-22       Impact factor: 5.082

Review 2.  From a Symptom-Based to a Mechanism-Based Pharmacotherapeutic Treatment in Complex Regional Pain Syndrome.

Authors:  Thomas J P Mangnus; Krishna D Bharwani; Maaike Dirckx; Frank J P M Huygen
Journal:  Drugs       Date:  2022-03-05       Impact factor: 11.431

3.  Neurosteroids and Seizure Activity.

Authors:  Barbara Miziak; Magdalena Chrościńska-Krawczyk; Stanisław J Czuczwar
Journal:  Front Endocrinol (Lausanne)       Date:  2020-09-30       Impact factor: 5.555

Review 4.  New Trends and Most Promising Therapeutic Strategies for Epilepsy Treatment.

Authors:  Antonella Riva; Alice Golda; Ganna Balagura; Elisabetta Amadori; Maria Stella Vari; Gianluca Piccolo; Michele Iacomino; Simona Lattanzi; Vincenzo Salpietro; Carlo Minetti; Pasquale Striano
Journal:  Front Neurol       Date:  2021-12-07       Impact factor: 4.003

  4 in total

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