Literature DB >> 3197754

Diurnal effects on debrisoquine hydroxylation phenotyping.

E J Lee1.   

Abstract

A study was performed to show whether debrisoquine phenotyping could be performed as an overnight procedure. Phenotyping of 33 normal volunteers was carried out during the day and night. A good correlation was observed between the day- and night-time metabolic ratios, although wide variation was observed in 3 subjects.

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Year:  1988        PMID： 3197754     DOI： 10.1007/bf00561381

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  5 in total

1.  Measurement of debrisoquine and 4-hydroxydebrisoquine in urine by liquid chromatography.

Authors:  E J Lee; S B Ang
Journal:  J Pharm Biomed Anal       Date:  1987       Impact factor: 3.935

2.  Genetically determined oxidation capacity and the disposition of debrisoquine.

Authors:  T P Sloan; R Lancaster; R R Shah; J R Idle; R L Smith
Journal:  Br J Clin Pharmacol       Date:  1983-04       Impact factor: 4.335

3.  The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions.

Authors:  D A Evans; D Harmer; D Y Downham; E J Whibley; J R Idle; J Ritchie; R L Smith
Journal:  J Med Genet       Date:  1983-10       Impact factor: 6.318

4.  Debrisoquine hydroxylation capacity: problems of assessment in two populations.

Authors:  T Inaba; S V Otton; W Kalow
Journal:  Clin Pharmacol Ther       Date:  1981-02       Impact factor: 6.875

5.  Polymorphic hydroxylation of Debrisoquine in man.

Authors:  A Mahgoub; J R Idle; L G Dring; R Lancaster; R L Smith
Journal:  Lancet       Date:  1977-09-17       Impact factor: 79.321
  5 in total
  1 in total

1.  Debrisoquine oxidation phenotype and susceptibility to lung cancer.

Authors:  A R Boobis; D S Davies
Journal:  Br J Clin Pharmacol       Date:  1990-10       Impact factor: 4.335
  1 in total

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