Ghodsi Mohammadi Ziarani1, Fatemeh Mohajer1, Zohreh Kheilkordi1.
Abstract
BACKGROUND: Natural products have been received attention due to their importance in human life as those are biologically active. In this review, there are some reports through different methods related to the synthesis of the indolizidine 195B which was extracted from poisonous frog; however, due to respect nature, the synthesis of natural compounds such as indolizidine has been attracted much attention among scientists and researchers.
OBJECTIVE: This review discloses the procedures and methods to provide indolizidine 195B from 1989 to 2018 due to their importance as a natural product.
CONCLUSION: There are several methods to give rise to the indolizidine 195B as a natural product that is highly active from the biological perspective in pharmaceutical chemistry. In summary, many protocols for the preparations of indolizidine 195B from various substrates, several reagents, and conditions have been reported from different aromatic and aliphatic. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
BACKGROUND: Natural products have been received attention due to their importance in human life as those are biologically active. In this review, there are some reports through different methods related to the synthesis of the indolizidine 195B which was extracted from poisonous frog; however, due to respect nature, the synthesis of natural compounds such as indolizidine has been attracted much attention among scientists and researchers.
OBJECTIVE: This review discloses the procedures and methods to provide indolizidine 195B from 1989 to 2018 due to their importance as a natural product.
CONCLUSION: There are several methods to give rise to the indolizidine 195B as a natural product that is highly active from the biological perspective in pharmaceutical chemistry. In summary, many protocols for the preparations of indolizidine 195B from various substrates, several reagents, and conditions have been reported from different aromatic and aliphatic. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.
Entities:
Keywords:
Natural products; alkaloids; aromatic groups; biologically active compounds; indolizidine 195B; poisonous frog.
Year: 2020
PMID： 31976841 DOI： 10.2174/1570179417666200124104010
Source DB: PubMed Journal: Curr Org Synth ISSN： 1570-1794 Impact factor: 1.975