| Literature DB >> 319767 |
Abstract
The "keratolytic" effect of salicylic acid was examined in guinea-pig skin. Using a fluorescent staining method the str. corneum cells could be seen to rapidly become detached. The cellular walls remained unchanged. This drug therefore appears to primarily reduce the intercellular cohesiveness of the horny cells.Entities:
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Year: 1977 PMID: 319767 DOI: 10.1007/bf00741846
Source DB: PubMed Journal: Arch Dermatol Res Impact factor: 3.017