Literature DB >> 3197448

Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31----q41.

M K Davidson1, M M Le Beau, R L Eddy, T B Shows, L A DiPietro, M Kingzette, W C Hanly.   

Abstract

Polymeric immunoglobulin receptor (PIGR) is a transmembrane glycoprotein which is expressed by epithelial cells and is involved in the transcellular transport of polymeric immunoglobulins into secretions. We cloned the human gene for PIGR and used the clone to obtain probes to determine the chromosomal localization of PIGR. Analysis of somatic cell hybrids and in situ chromosomal hybridization localized the human PIGR gene locus to 1q31----q41.

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Year:  1988        PMID： 3197448     DOI： 10.1159/000132601

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  3 in total

1.  The human transmembrane secretory component (poly-Ig receptor): molecular cloning, restriction fragment length polymorphism and chromosomal sublocalization.

Authors:  P Krajci; K H Grzeschik; A H Geurts van Kessel; B Olaisen; P Brandtzaeg
Journal:  Hum Genet       Date:  1991-10       Impact factor: 4.132

2.  The gene encoding human transmembrane secretory component (locus PIGR) is linked to D1S58 on chromosome 1.

Authors:  P Krajci; T Gedde-Dahl; B Høyheim; S Rogde; B Olaisen; P Brandtzaeg
Journal:  Hum Genet       Date:  1992-11       Impact factor: 4.132

3.  Secretory component mRNA and protein expression in colorectal adenomas and carcinomas.

Authors:  P Krajci; G I Meling; S N Andersen; B Hofstad; M H Vatn; T O Rognum; P Brandtzaeg
Journal:  Br J Cancer       Date:  1996-06       Impact factor: 7.640
  3 in total

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