Literature DB >> 31974168

Avapritinib Approved for GIST Subgroup.

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Abstract

The FDA approved avapritinib for the treatment of unresectable or metastatic gastrointestinal stromal tumors with mutations in exon 18 of PDGFRA-genetic alterations that render tumors insensitive to all previously approved therapies for this rare sarcoma of the digestive tract. ©2020 American Association for Cancer Research.

Entities:  

Year:  2020        PMID: 31974168     DOI: 10.1158/2159-8290.CD-NB2020-002

Source DB:  PubMed          Journal:  Cancer Discov        ISSN: 2159-8274            Impact factor:   39.397


  6 in total

1.  DICER1-Associated Anaplastic Sarcoma of the Kidney With Coexisting Activating PDGFRA D842V Mutations and Response to Targeted Kinase Inhibitors in One Patient.

Authors:  Cristina R Antonescu; Victor E Reuter; Mary Lou Keohan; Sinchun Hwang; Ping Chi
Journal:  JCO Precis Oncol       Date:  2022-07

Review 2.  The Molecular Biology of Soft Tissue Sarcomas: Current Knowledge and Future Perspectives.

Authors:  Julien Vibert; Sarah Watson
Journal:  Cancers (Basel)       Date:  2022-05-22       Impact factor: 6.575

Review 3.  Small molecules in targeted cancer therapy: advances, challenges, and future perspectives.

Authors:  Lei Zhong; Yueshan Li; Liang Xiong; Wenjing Wang; Ming Wu; Ting Yuan; Wei Yang; Chenyu Tian; Zhuang Miao; Tianqi Wang; Shengyong Yang
Journal:  Signal Transduct Target Ther       Date:  2021-05-31

4.  Extragastrointestinal Stromal Tumor Presenting as a Recurrent Vaginal Mass: Case Report.

Authors:  Shuai Liu; Pan Pan; Bing Han; Jingnan Wang; Meili Sun; Yuping Sun
Journal:  Onco Targets Ther       Date:  2021-02-10       Impact factor: 4.147

5.  Inhibition of KIT Tyrosine Kinase Activity: Two Decades After the First Approval.

Authors:  Lillian R Klug; Christopher L Corless; Michael C Heinrich
Journal:  J Clin Oncol       Date:  2021-04-02       Impact factor: 44.544

Review 6.  Strategies for care of patients with gastrointestinal stromal tumor or soft tissue sarcoma during COVID-19 pandemic: A guide for surgical oncologists.

Authors:  Dario Callegaro; Chandrajit P Raut; Emily Z Keung; Teresa Kim; Cecile Le Pechoux; Javier Martin-Broto; Alessandro Gronchi; Carol Swallow; Rebecca Gladdy
Journal:  J Surg Oncol       Date:  2020-10-06       Impact factor: 2.885

  6 in total

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