Literature DB >> 31973278

Chemically Modified Diatoms Biosilica for Bone Cell Growth with Combined Drug-Delivery and Antioxidant Properties.

Stefania R Cicco1, Danilo Vona2, Elvira De Giglio2, Stefania Cometa3, Monica Mattioli-Belmonte4, Fabio Palumbo5, Roberta Ragni2, Gianluca M Farinola1,2.   

Abstract

Nanostructured biosilica produced by Thalassiosira weissflogii diatoms is covalently functionalized with the cyclic nitroxide 2,6,6-tetramethylpiperidine-N-oxyl (TEMPO), an efficient scavenger of reactive oxygen species (ROS) in biological systems. Drug delivery properties of the TEMPO-functionalized biosilica are studied for Ciprofloxacin, an antimicrobial thoroughly employed in orthopedic or dental implant related infections. The resulting TEMPO-biosilica, combining Ciprofloxacin drug delivery with anti-oxidant properties, is demonstrated to be a suitable material for fibroblasts and osteoblast-like cells growth.
Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  TEMPO; biomaterials; biosilica; diatoms; drug delivery

Year:  2015        PMID： 31973278     DOI： 10.1002/cplu.201402398

Source DB:  PubMed          Journal:  Chempluschem        ISSN： 2192-6506            Impact factor:   2.863


  7 in total

1.  Polydopamine coating of living diatom microalgae.

Authors:  Danilo Vona; Stefania R Cicco; Roberta Ragni; Cesar Vicente-Garcia; Gabriella Leone; Maria Michela Giangregorio; Fabio Palumbo; Emiliano Altamura; Gianluca M Farinola
Journal:  Photochem Photobiol Sci       Date:  2022-02-14       Impact factor: 4.328

Review 2.  Microalgae: therapeutic potentials and applications.

Authors:  Fatemeh Khavari; Massoud Saidijam; Mohammad Taheri; Fatemeh Nouri
Journal:  Mol Biol Rep       Date:  2021-05-24       Impact factor: 2.316

3.  Incorporating a molecular antenna in diatom microalgae cells enhances photosynthesis.

Authors:  Gabriella Leone; Gabriel De la Cruz Valbuena; Stefania Roberta Cicco; Danilo Vona; Emiliano Altamura; Roberta Ragni; Egle Molotokaite; Michela Cecchin; Stefano Cazzaniga; Matteo Ballottari; Cosimo D'Andrea; Guglielmo Lanzani; Gianluca Maria Farinola
Journal:  Sci Rep       Date:  2021-03-04       Impact factor: 4.379

Review 4.  Novel Drug and Gene Delivery System and Imaging Agent Based on Marine Diatom Biosilica Nanoparticles.

Authors:  Hanaa Ali Hussein; Muhammad Shahid Nazir; Nizakat Azra; Zeenat Qamar; Azman Seeni; Tengku Ahmad Damitri Al-Astani Tengku Din; Mohd Azmuddin Abdullah
Journal:  Mar Drugs       Date:  2022-07-27       Impact factor: 6.085

Review 5.  Photonic Nano-/Microstructured Diatom Based Biosilica in Metal Modification and Removal-A Review.

Authors:  Piya Roychoudhury; Rahul Bose; Przemysław Dąbek; Andrzej Witkowski
Journal:  Materials (Basel)       Date:  2022-09-23       Impact factor: 3.748

6.  Photoactivatable Surface-Functionalized Diatom Microalgae for Colorectal Cancer Targeted Delivery and Enhanced Cytotoxicity of Anticancer Complexes.

Authors:  Joachim Delasoie; Philippe Schiel; Sandra Vojnovic; Jasmina Nikodinovic-Runic; Fabio Zobi
Journal:  Pharmaceutics       Date:  2020-05-25       Impact factor: 6.321

7.  Preparation and characterization of diatomite and hydroxyapatite reinforced porous polyurethane foam biocomposites.

Authors:  Sibel Demiroglu Mustafov; Fatih Sen; M Ozgur Seydibeyoglu
Journal:  Sci Rep       Date:  2020-08-06       Impact factor: 4.379
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.