| Literature DB >> 31970683 |
Antonio Mangieri1, Francesco Gallo2, Alessandro Sticchi2, Arif A Khokhar2, Alessandra Laricchia2, Francesco Giannini2, Antonio Colombo2.
Abstract
Antiplatelet therapy, the cornerstone of post coronary stenting antithrombotic therapy, reduces the rate of hard clinical endpoints in patients treated both conservatively and invasively following an acute coronary syndrome, as well as in those patients with chronic stable coronary disease who receive a coronary stent. The development of newer antiplatelet and direct anticoagulant agents provides new options in the antithrombotic management of patients with coronary artery disease, enabling different therapeutic combinations to be tailored to an individual patient's bleeding and ischemic risk profile. In this review, we will summarize the history of dual antiplatelet therapy, discuss the latest evidence and future perspectives in treating patients with coronary artery disease.Entities:
Keywords: Acute coronary syndromes; Aspirin; Bleeding; Direct oral anticoagulants; Dual antiplatelet therapy; Myocardial infarction; P2Y12 inhibitors; Stent thrombosis
Year: 2020 PMID: 31970683 DOI: 10.1007/s12928-020-00642-w
Source DB: PubMed Journal: Cardiovasc Interv Ther ISSN: 1868-4297