Kye Won Park1, Nari Choi1, Ho-Sung Ryu2, Ho Jin Kim3, Chong S Lee1, Sun Ju Chung1. 1. Department of Neurology Asan Medical Center, University of Ulsan College of Medicine Seoul South Korea. 2. Department of Neurology Kyungpook National University School of Medicine Daegu South Korea. 3. Department of Thoracic and Cardiovascular Surgery Asan Medical Center, University of Ulsan College of Medicine Seoul South Korea.
Abstract
BACKGROUND: Post-pump chorea and progressive-supranuclear palsy (PSP)-like syndrome after aortic surgery are 2 distinct movement disorders following major cardiac surgeries. CASES: We herein report 3 patients with movement disorders that developed after major cardiac surgeries. Two patients developed post-pump chorea after pulmonary endarterectomy, and 1 further case developed PSP-like syndrome after aortic replacement surgery. The 2 conditions share several common aspects. Both are preceded by surgeries that undergo cardiopulmonary bypass and deep hypothermia circulatory arrest procedures. Most cases present with biphasic course. However, post-pump chorea occurs in all age populations after any surgeries that undergo deep hypothermia circulatory arrest, whereas PSP-like syndrome is reported exclusively in the adult population after aortic surgery. CONCLUSIONS: Post-pump chorea and PSP-like syndrome are neurologic complications of major cardiac surgeries that should not be underrecognized. Further reports to establish their common pathogenic mechanism should be encouraged.
BACKGROUND: Post-pump chorea and progressive-supranuclear palsy (PSP)-like syndrome after aortic surgery are 2 distinct movement disorders following major cardiac surgeries. CASES: We herein report 3 patients with movement disorders that developed after major cardiac surgeries. Two patients developed post-pump chorea after pulmonary endarterectomy, and 1 further case developed PSP-like syndrome after aortic replacement surgery. The 2 conditions share several common aspects. Both are preceded by surgeries that undergo cardiopulmonary bypass and deep hypothermia circulatory arrest procedures. Most cases present with biphasic course. However, post-pump chorea occurs in all age populations after any surgeries that undergo deep hypothermia circulatory arrest, whereas PSP-like syndrome is reported exclusively in the adult population after aortic surgery. CONCLUSIONS: Post-pump chorea and PSP-like syndrome are neurologic complications of major cardiac surgeries that should not be underrecognized. Further reports to establish their common pathogenic mechanism should be encouraged.
Authors: Sulaiman Surie; Marina A J Tijssen; Jules D Biervliet; Edouard M de Beaumont; Jaap J Kloek; Peter M M J Rutten; Harriet M M Smeding; Paul Bresser; Rob M A de Bie Journal: Mov Disord Date: 2010-06-15 Impact factor: 10.338
Authors: Dara Ditsworth; Margaret A Priestley; Andreas W Loepke; Chandra Ramamoorthy; John McCann; Lauren Staple; C Dean Kurth Journal: Anesthesiology Date: 2003-05 Impact factor: 7.892
Authors: P C Wong; C F Barlow; P R Hickey; R A Jonas; A R Castaneda; D M Farrell; J E Lock; D L Wessel Journal: Circulation Date: 1992-11 Impact factor: 29.690
Authors: Scott D Z Eggers; Anja K E Horn; Sigrun Roeber; Wolfgang Härtig; Govind Nair; Daniel S Reich; R John Leigh Journal: PLoS One Date: 2015-07-02 Impact factor: 3.240