Literature DB >> 3196929

In vitro steroid metabolism by rat retina.

A Lanthier1, V V Patwardhan.   

Abstract

We have previously detected progesterone, dehydroepiandrosterone, androstenedione, testosterone and estrone in rat retina. The present experiments show that the presence of these steroids in the retina may not be due to local biosynthesis. On the other hand, they demonstrate considerable 5 alpha-reductase and 3 beta-hydroxysteroid dehydrogenase activities in the rat retina. The significance of these activities in the retina is discussed.

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Year:  1988        PMID: 3196929     DOI: 10.1016/0006-8993(88)90419-2

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  8 in total

1.  Identification of androgen receptor protein and 5alpha-reductase mRNA in human ocular tissues.

Authors:  E M Rocha; L A Wickham; L A da Silveira; K L Krenzer; F S Yu; I Toda; B D Sullivan; D A Sullivan
Journal:  Br J Ophthalmol       Date:  2000-01       Impact factor: 4.638

2.  TESTOSTERONE SUPPLEMENTATION AND RETINAL VASCULAR DISEASE.

Authors:  Vaidehi S Dedania; David N Zacks; Wei Pan; Brian L VanderBeek
Journal:  Retina       Date:  2018-11       Impact factor: 4.256

3.  Progesterone treatment in two rat models of ocular ischemia.

Authors:  Rachael S Allen; Timothy W Olsen; Iqbal Sayeed; Heather A Cale; Katherine C Morrison; Yuliya Oumarbaeva; Irina Lucaciu; Jeffrey H Boatright; Machelle T Pardue; Donald G Stein
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-05       Impact factor: 4.799

4.  ATP-binding cassette transporter G2 mediates the efflux of phototoxins on the luminal membrane of retinal capillary endothelial cells.

Authors:  Tomoko Asashima; Satoko Hori; Sumio Ohtsuki; Masanori Tachikawa; Masahiko Watanabe; Chisato Mukai; Shinji Kitagaki; Naoki Miyakoshi; Tetsuya Terasaki
Journal:  Pharm Res       Date:  2006-05-25       Impact factor: 4.200

5.  Progesterone treatment shows greater protection in brain vs. retina in a rat model of middle cerebral artery occlusion: Progesterone receptor levels may play an important role.

Authors:  Rachael S Allen; Iqbal Sayeed; Yuliya Oumarbaeva; Katherine C Morrison; Paul H Choi; Machelle T Pardue; Donald G Stein
Journal:  Restor Neurol Neurosci       Date:  2016-11-22       Impact factor: 2.406

Review 6.  Neuroprotective strategies for retinal disease.

Authors:  Machelle T Pardue; Rachael S Allen
Journal:  Prog Retin Eye Res       Date:  2018-02-23       Impact factor: 21.198

7.  The goldfish as a model for studying neuroestrogen synthesis, localization, and action in the brain and visual system.

Authors:  G V Callard; A Kruger; M Betka
Journal:  Environ Health Perspect       Date:  1995-10       Impact factor: 9.031

8.  Androgen Deprivation Therapy for Prostate Cancer Did Not Increase the Risk of Retinal Vascular Occlusion: A Population-Based Cohort Study.

Authors:  Hsin-Le Lin; Chia-Yi Lee; Jing-Yang Huang; Po-Chen Tseng; Shun-Fa Yang
Journal:  Int J Environ Res Public Health       Date:  2022-02-17       Impact factor: 3.390

  8 in total

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