Literature DB >> 3196922

Lamina-specific arrangement of astrocytic gliosis and senile plaques in Alzheimer's disease visual cortex.

T G Beach1, E G McGeer.   

Abstract

Alzheimer's disease (AD) visual cortex (area 17) was investigated using stains for plaques and tangles (Bielschowsky, thioflavine S) and gliosis (GFAP immunoperoxidase). Pathology was heaviest in layers II, III, IVa and IVc. Of especial interest was a thin line of plaques and astrocytic gliosis at the lower margin of layer IVc. These results could provide an insight into the pathogenesis of AD, and suggest that patients with AD may have specific visual deficits.

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Year:  1988        PMID： 3196922     DOI： 10.1016/0006-8993(88)90410-6

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  36 in total

1.  Senile plaques, amyloid beta-protein, and acetylcholinesterase fibres: laminar distributions in Alzheimer's disease striate cortex.

Authors:  T G Beach; E G McGeer
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

2.  Involvement of perineuronal and perisynaptic extracellular matrix in Alzheimer's disease neuropathology.

Authors:  Markus Morawski; Gert Brückner; Carsten Jäger; Gudrun Seeger; Russel T Matthews; Thomas Arendt
Journal:  Brain Pathol       Date:  2012-01-13       Impact factor: 6.508

Review 3.  Translational potential of astrocytes in brain disorders.

Authors:  Alexei Verkhratsky; Luca Steardo; Vladimir Parpura; Vedrana Montana
Journal:  Prog Neurobiol       Date:  2015-09-16       Impact factor: 11.685

4.  The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease.

Authors:  M Kawai; R N Kalaria; S I Harik; G Perry
Journal:  Am J Pathol       Date:  1990-12       Impact factor: 4.307

5.  Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees.

Authors:  Emily L Munger; Melissa K Edler; William D Hopkins; John J Ely; Joseph M Erwin; Daniel P Perl; Elliott J Mufson; Patrick R Hof; Chet C Sherwood; Mary Ann Raghanti
Journal:  J Comp Neurol       Date:  2019-01-07       Impact factor: 3.215

6.  Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease.

Authors:  Malia M Edwards; José J Rodríguez; Raquel Gutierrez-Lanza; Joseph Yates; Alexei Verkhratsky; Gerard A Lutty
Journal:  Exp Eye Res       Date:  2014-08-19       Impact factor: 3.467

7.  PATHOBIOLOGY OF NEURODEGENERATION: THE ROLE FOR ASTROGLIA.

Authors:  Alexei Verkhratsky; Robert Zorec; Jose J Rodriguez; Vladimir Parpura
Journal:  Opera Med Physiol       Date:  2016-03-04

8.  Myelinated axon number in the optic nerve is unaffected by Alzheimer's disease.

Authors:  D C Davies; P McCoubrie; B McDonald; K A Jobst
Journal:  Br J Ophthalmol       Date:  1995-06       Impact factor: 4.638

9.  Columnar arrangement of beta-amyloid protein deposits in the cerebral cortex of patients with Alzheimer's disease.

Authors:  H Akiyama; T Yamada; P L McGeer; T Kawamata; I Tooyama; T Ishii
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

10.  Astroglial Vesicular Trafficking in Neurodegenerative Diseases.

Authors:  Robert Zorec; Vladimir Parpura; Alexei Verkhratsky
Journal:  Neurochem Res       Date:  2016-09-14       Impact factor: 3.996
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