Literature DB >> 3196760

The metabolism of 1-methylhydantoin via 5-hydroxy-1-methylhydantoin in mammals.

K Ienaga1, K Nakamura, F Naka, T Goto.   

Abstract

The metabolic pathway of 1-methylhydantoin (2) via 5-hydroxy-1-methylhydantoin (3), methylparabanic acid (4) and N5-methyloxaluric acid (5) proved to be a major and general one in mammals. Hence the formation of (3), which has not been detected in normal tissue, is likely to be indirect in inflamed tissue, probably depending on the arising formation of (2) from creatinine (1).

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Year:  1988        PMID: 3196760     DOI: 10.1016/0304-4165(88)90108-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  2 in total

1.  Creatol (5-hydroxycreatinine), a new toxin candidate in uremic patients.

Authors:  K Nakamura; K Ienaga
Journal:  Experientia       Date:  1990-05-15

2.  Protective mechanism of 1-methylhydantoin against lung injury induced by paraquat poisoning.

Authors:  Bo Liu; Annan Chen; Jinyi Lan; Lei Ren; Yifan Wei; Lina Gao
Journal:  PLoS One       Date:  2019-09-27       Impact factor: 3.240

  2 in total

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