Literature DB >> 31967048

BILATERAL NEUROARTHROPATHY 11 YEARS AFTER SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANT FOR TYPE 1 DIABETES MELLITUS.

Sebastian Ho, Jasdeep Giddie, Ketan K Dhatariya.   

Abstract

OBJECTIVE: To report a case of a man who developed bilateral Charcot arthropathic feet 11 years after a simultaneous pancreas-kidney transplant (SPKT) for type 1 diabetes mellitus (DM). The patient had remained normoglycemic after surgery.
METHODS: We present a retrospective review of the case notes and serial imaging.
RESULTS: The patient developed dense peripheral diabetic neuropathy due to poor glycemic control. His biochemical markers of DM all normalized following SPKT, and he was discharged by his primary and secondary care diabetes services. Eleven years later, he developed Charcot arthropathy in one foot and, within a month, the other foot as well.
CONCLUSION: Individuals with DM who had preoperative end organ diabetes-related damage who went into biochemical remission after SPKT may be at risk for future complications. They should not be discharged from specialist diabetes services, and they need continued education about foot care.
Copyright © 2019 AACE.

Entities:  

Year:  2019        PMID: 31967048      PMCID: PMC6873833          DOI: 10.4158/ACCR-2018-0408

Source DB:  PubMed          Journal:  AACE Clin Case Rep        ISSN: 2376-0605


  11 in total

Review 1.  The role of proinflammatory cytokines in the cause of neuropathic osteoarthropathy (acute Charcot foot) in diabetes.

Authors:  William J Jeffcoate; Fran Game; Peter R Cavanagh
Journal:  Lancet       Date:  2005-08-10       Impact factor: 79.321

2.  High rate of Charcot foot attacks early after simultaneous pancreas-kidney transplantation.

Authors:  Giovanni A Matricali; Bert Bammens; Dirk Kuypers; Maria Flour; Chantal Mathieu
Journal:  Transplantation       Date:  2007-01-27       Impact factor: 4.939

Review 3.  Charcot foot syndrome.

Authors:  W J Jeffcoate
Journal:  Diabet Med       Date:  2015-04-15       Impact factor: 4.359

4.  Charcot neuroarthropathy after simultaneous pancreas-kidney transplantation: risk factors, prevalence, and outcome.

Authors:  Fernando García Barrado; Dirk R Kuypers; Giovanni A Matricali
Journal:  Clin Transplant       Date:  2015-07-14       Impact factor: 2.863

5.  Charcot neuroarthropathy after simultaneous pancreas-kidney transplant.

Authors:  Érika B Rangel; João R Sá; Samirah A Gomes; Aluizio B Carvalho; Cláudio S Melaragno; Adriano M Gonzalez; Marcelo M Linhares; Jose O Medina-Pestana
Journal:  Transplantation       Date:  2012-09-27       Impact factor: 4.939

Review 6.  Neurotoxicity of calcineurin inhibitors: impact and clinical management.

Authors:  W O Bechstein
Journal:  Transpl Int       Date:  2000       Impact factor: 3.782

7.  The development of a charcot foot after significant weight loss in people with diabetes: three cautionary tales.

Authors:  Rachel Murchison; Catherine Gooday; Ketan Dhatariya
Journal:  J Am Podiatr Med Assoc       Date:  2014 Sep-Oct

8.  Pedal neuroarthropathy in a nondiabetic patient as a result of long-term amiodarone use.

Authors:  Ketan Dhatariya; Catherine Gooday; Rachel Murchison; Benjamin Bullen; Rachael Hutchinson
Journal:  J Foot Ankle Surg       Date:  2009 May-Jun       Impact factor: 1.286

9.  Charcot neuroarthropathy in simultaneous kidney-pancreas transplantation: report of two cases.

Authors:  Jorge Javier Del Vecchio; Nicolás Raimondi; Horacio Rivarola; Carlos Autorino
Journal:  Diabet Foot Ankle       Date:  2013-08-29

Review 10.  Simultaneous pancreas and kidney transplantation: current trends and future directions.

Authors:  Robert R Redfield; Joseph R Scalea; Jon S Odorico
Journal:  Curr Opin Organ Transplant       Date:  2015-02       Impact factor: 2.640

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