Literature DB >> 3196659

Quantitative histological analysis of antigen-induced arthritis in the rabbit.

J C Edwards1, N Read, B Trefty, J Coulstock, B Henderson.   

Abstract

Antigen-induced arthritis in the rabbit (AIAR) provides the closest experimental equivalent to human rheumatoid arthritis in terms of infiltration of synovial tissue by lymphoid cells. A method is described for quantitative histological analysis of AIAR. Measurements of total cell numbers, lymphocyte and polymorphonuclear leucocyte infiltration, and thickness of infiltrated synovium were obtained for ranges of antigen dosage and duration of arthritis. The method has been devised as part of a system for the analysis of joint swelling, synovial fluid biochemistry and cytology, cartilage proteoglycan chemistry and synovial histology on the same specimen.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3196659      PMCID： PMC2013267     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  5 in total

1.  The production of arthritis in rabbits by an immunological reaction to fibrin.

Authors:  D C DUMONDE; L E GLYNN
Journal:  Br J Exp Pathol       Date:  1962-08

2.  Synthesis of arachidonate oxidation products by synovial joint tissues during the development of chronic erosive arthritis.

Authors:  B Henderson; G A Higgs
Journal:  Arthritis Rheum       Date:  1987-10

3.  Preparation of whole rabbit knee joints for microscopic examination.

Authors:  C Ohrt; M L Mahowald; A A Valls
Journal:  Stain Technol       Date:  1986-11

4.  Local cell populations in experimental arthritides.

Authors:  A T Doble
Journal:  Agents Actions       Date:  1986-12

5.  Interleukin 1 induces leukocyte infiltration and cartilage proteoglycan degradation in the synovial joint.

Authors:  E R Pettipher; G A Higgs; B Henderson
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205
  5 in total
  6 in total

1.  Effect of indomethacin on swelling, lymphocyte influx, and cartilage proteoglycan depletion in experimental arthritis.

Authors:  E R Pettipher; B Henderson; J C Edwards; G A Higgs
Journal:  Ann Rheum Dis       Date:  1989-08       Impact factor: 19.103

2.  Pathogenesis of antigen-induced arthritis in mice deficient in neutrophil elastase and cathepsin G.

Authors:  R Pettipher; J Edwards; S Cruwys; E Jessup; J Beesley; B Henderson
Journal:  Am J Pathol       Date:  1990-11       Impact factor: 4.307

3.  Direct adenovirus-mediated gene transfer of interleukin 1 and tumor necrosis factor alpha soluble receptors to rabbit knees with experimental arthritis has local and distal anti-arthritic effects.

Authors:  S C Ghivizzani; E R Lechman; R Kang; C Tio; J Kolls; C H Evans; P D Robbins
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-14       Impact factor: 11.205

4.  Antifibrotic action of interleukin-1 receptor antagonist in lapine monoarticular arthritis.

Authors:  J Lewthwaite; S Blake; R C Thompson; T E Hardingham; B Henderson
Journal:  Ann Rheum Dis       Date:  1995-07       Impact factor: 19.103

5.  Experimental arthritis induced by continuous infusion of IL-8 into rabbit knee joints.

Authors:  H Endo; T Akahoshi; A Nishimura; M Tonegawa; K Takagishi; S Kashiwazaki; K Matsushima; H Kondo
Journal:  Clin Exp Immunol       Date:  1994-04       Impact factor: 4.330

6.  Involvement of platelet-activating factor and tumour necrosis factor in the pathogenesis of joint inflammation in rabbits.

Authors:  P Zarco; C Maestre; G Herrero-Beaumont; E González; R Garcia-Hoyo; F J Navarro; P Braquet; J Egido
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.