Literature DB >> 31965523

On-Demand Oral Pre-exposure Prophylaxis with Tenofovir/Emtricitabine: What Every Clinician Needs to Know.

Parya Saberi1, Hyman M Scott2.   

Abstract

Based on the results of the IPERGAY study, on-demand HIV pre-exposure prophylaxis (PrEP; also known as "non-daily PrEP," "event-driven PrEP," or "2-1-1 PrEP") is being requested more frequently by patients who have intermittent sexual risk or are unable/unwilling to take daily PrEP; therefore, clinicians will be increasingly required to familiarize themselves with its appropriate use. In this perspective, we summarize data related to on-demand PrEP, describe advantages and disadvantages for this alternative dosing strategy, and provide clinical counseling points.

Entities:  

Keywords:  2-1-1; PrEP; clinician; on-demand; pre-exposure prophylaxis; tenofovir/emtricitabine

Mesh：

Substances：

Year:  2020        PMID： 31965523      PMCID： PMC7174437          DOI： 10.1007/s11606-020-05651-2

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN： 0884-8734            Impact factor:   5.128


  23 in total

1.  Sexual frequency and planning among at-risk men who have sex with men in the United States: implications for event-based intermittent pre-exposure prophylaxis.

Authors:  Jonathan E Volk; Albert Liu; Eric Vittinghoff; Risha Irvin; Elizabeth Kroboth; Douglas Krakower; Matthew J Mimiaga; Kenneth H Mayer; Patrick S Sullivan; Susan P Buchbinder
Journal:  J Acquir Immune Defic Syndr       Date:  2012-09-01       Impact factor: 3.731

2.  Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.

Authors:  Robert M Grant; Javier R Lama; Peter L Anderson; Vanessa McMahan; Albert Y Liu; Lorena Vargas; Pedro Goicochea; Martín Casapía; Juan Vicente Guanira-Carranza; Maria E Ramirez-Cardich; Orlando Montoya-Herrera; Telmo Fernández; Valdilea G Veloso; Susan P Buchbinder; Suwat Chariyalertsak; Mauro Schechter; Linda-Gail Bekker; Kenneth H Mayer; Esper Georges Kallás; K Rivet Amico; Kathleen Mulligan; Lane R Bushman; Robert J Hance; Carmela Ganoza; Patricia Defechereux; Brian Postle; Furong Wang; J Jeff McConnell; Jia-Hua Zheng; Jeanny Lee; James F Rooney; Howard S Jaffe; Ana I Martinez; David N Burns; David V Glidden
Journal:  N Engl J Med       Date:  2010-11-23       Impact factor: 91.245

3.  Impairment in kidney tubular function in patients receiving tenofovir is associated with higher tenofovir plasma concentrations.

Authors:  Sonia Rodríguez-Nóvoa; Pablo Labarga; Antonio D'avolio; Pablo Barreiro; Marta Albalate; Eugenia Vispo; Carmen Solera; Marco Siccardi; Stefano Bonora; Giovanni Di Perri; Vincent Soriano
Journal:  AIDS       Date:  2010-04-24       Impact factor: 4.177

4.  Integrating HIV Preexposure Prophylaxis (PrEP) Into Routine Preventive Health Care to Avoid Exacerbating Disparities.

Authors:  Sarah K Calabrese; Douglas S Krakower; Kenneth H Mayer
Journal:  Am J Public Health       Date:  2017-10-19       Impact factor: 9.308

5.  Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men.

Authors:  Peter L Anderson; David V Glidden; Albert Liu; Susan Buchbinder; Javier R Lama; Juan Vicente Guanira; Vanessa McMahan; Lane R Bushman; Martín Casapía; Orlando Montoya-Herrera; Valdilea G Veloso; Kenneth H Mayer; Suwat Chariyalertsak; Mauro Schechter; Linda-Gail Bekker; Esper Georges Kallás; Robert M Grant
Journal:  Sci Transl Med       Date:  2012-09-12       Impact factor: 17.956

6.  Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults: 2018 Recommendations of the International Antiviral Society-USA Panel.

Authors:  Michael S Saag; Constance A Benson; Rajesh T Gandhi; Jennifer F Hoy; Raphael J Landovitz; Michael J Mugavero; Paul E Sax; Davey M Smith; Melanie A Thompson; Susan P Buchbinder; Carlos Del Rio; Joseph J Eron; Gerd Fätkenheuer; Huldrych F Günthard; Jean-Michel Molina; Donna M Jacobsen; Paul A Volberding
Journal:  JAMA       Date:  2018-07-24       Impact factor: 56.272

7.  Pleasure and PrEP: Pleasure-Seeking Plays a Role in Prevention Choices and Could Lead to PrEP Initiation.

Authors:  Xavier Mabire; Costanza Puppo; Stéphane Morel; Marion Mora; Daniela Rojas Castro; Julie Chas; Eric Cua; Claire Pintado; Marie Suzan-Monti; Bruno Spire; Jean-Michel Molina; Marie Préau
Journal:  Am J Mens Health       Date:  2019 Jan-Feb

8.  Motives for choosing, switching and stopping daily or event-driven pre-exposure prophylaxis - a qualitative analysis.

Authors:  Hanne Ml Zimmermann; Sanne W Eekman; Roel Ca Achterbergh; Maarten F Schim van der Loeff; Maria Prins; Henry Jc de Vries; Elske Hoornenborg; Udi Davidovich
Journal:  J Int AIDS Soc       Date:  2019-10       Impact factor: 5.396

9.  Drug-drug interactions between feminizing hormone therapy and pre-exposure prophylaxis among transgender women: the iFACT study.

Authors:  Akarin Hiransuthikul; Rena Janamnuaysook; Kanittha Himmad; Stephen J Kerr; Narukjaporn Thammajaruk; Tippawan Pankam; Kannapat Phanjaroen; Stephen Mills; Ravipa Vannakit; Praphan Phanuphak; Nittaya Phanuphak
Journal:  J Int AIDS Soc       Date:  2019-07       Impact factor: 5.396

10.  HIV Preexposure Prophylaxis, by Race and Ethnicity - United States, 2014-2016.

Authors:  Ya-Lin A Huang; Weiming Zhu; Dawn K Smith; Norma Harris; Karen W Hoover
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2018-10-19       Impact factor: 17.586
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  6 in total

1.  Projected Impact of Expanded Long-Acting Injectable PrEP Use Among Men Who Have Sex With Men on Local HIV Epidemics.

Authors:  Ruchita Balasubramanian; Parastu Kasaie; Melissa Schnure; David W Dowdy; Maunank Shah; Anthony Todd Fojo
Journal:  J Acquir Immune Defic Syndr       Date:  2022-10-01       Impact factor: 3.771

Review 2.  Delayed presentation of HIV among older individuals: a growing problem.

Authors:  Amy C Justice; Matthew B Goetz; Cameron N Stewart; Brenna C Hogan; Elizabeth Humes; Paula M Luz; Jessica L Castilho; Denis Nash; Ellen Brazier; Beverly Musick; Constantin Yiannoutsos; Karen Malateste; Antoine Jaquet; Morna Cornell; Tinei Shamu; Reena Rajasuriar; Awachana Jiamsakul; Keri N Althoff
Journal:  Lancet HIV       Date:  2022-02-23       Impact factor: 16.070

3.  PrEP Willingness and Adherence Self-Efficacy Among Men Who have Sex with Men with Recent Condomless Anal Sex in Urban China.

Authors:  Shufang Sun; Cui Yang; Nickolas Zaller; Zhihua Zhang; Hongbo Zhang; Don Operario
Journal:  AIDS Behav       Date:  2021-05-01

4.  HIV Preexposure Prophylaxis in the Time of COVID-19: How a Robust and Responsive HIV Preexposure Prophylaxis Intervention Can Avert Loss of HIV Prevention Coverage During a Global Pandemic.

Authors:  Parya Saberi; Kristin Ming; J Carlo Hojilla; Hyman M Scott; Torsten B Neilands
Journal:  J Acquir Immune Defic Syndr       Date:  2021-05-01       Impact factor: 3.771

5.  Changes in Utilization of Birth Control and PrEP During COVID-19 in the USA: A Mixed-Method Analysis.

Authors:  Rachel A Fikslin; Alison J Goldberg; Amanda N Gesselman; Mora A Reinka; Omaima Pervez; Elissia T Franklin; Olivia Ahn; Devon M Price
Journal:  Arch Sex Behav       Date:  2021-11-08

6.  Temporal Variation in One-Time Partnership Rates Among Young Men Who Have Sex With Men and Transgender Women.

Authors:  Patrick Janulis; Steven M Goodreau; Michelle Birkett; Gregory Phillips; Martina Morris; Brian Mustanski; Samuel M Jenness
Journal:  J Acquir Immune Defic Syndr       Date:  2021-07-01       Impact factor: 3.771
  6 in total

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