| Literature DB >> 31965126 |
Qingqing Xiong1, Yujing Li2, Kun Zhou3, Ping Chen4, Hua Guo5, Lu Chen4, Jianxun Ding6, Tianqiang Song4, Jinjun Shi2.
Abstract
Six cationic lipidoid fluorodendrimers are synthesized to construct hybrid lipid-polymer nanoparticles for siRNA delivery. By screening the nanoplatforms including fluorodendrimers with different chemical structures, the optimized nanoparticle NPF13-5 mediates the most efficient silencing of prohibitin 1, inhibition of cell proliferation, and induction of cell apoptosis towards A549 lung adenocarcinoma cells.Entities:
Year: 2020 PMID： 31965126 DOI： 10.1039/c9bm01738k
Source DB: PubMed Journal: Biomater Sci ISSN： 2047-4830 Impact factor: 6.843