Literature DB >> 3196346

Synthetic ferrichrome analogues with growth promotion activity for Arthrobacter flavescens.

A Shanzer1, J Libman, R Lazar, Y Tor, T Emery.   

Abstract

Two families of trihydroxamic acid analogues of ferrichrome were chemically synthesized and tested for biological activity with Arthrobacter flavescens. Compounds using a tertiary amine as anchor showed little activity. Several compounds using tetrahedral carbon as anchor showed activity approaching or equalling that of the natural siderophore, ferrichrome. The biological activity is discussed in relation to physical and chemical properties of the analogues.

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Year:  1988        PMID： 3196346     DOI： 10.1016/s0006-291x(88)80059-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  2 in total

1.  Chiral linear hydroxamates as biomimetic analogues of ferrioxamine and coprogen and their use in probing siderophore-receptor specificity in bacteria and fungi.

Authors:  I Berner; P Yakirevitch; J Libman; A Shanzer; G Winkelmann
Journal:  Biol Met       Date:  1991

2.  Iron uptake and molecular recognition in Pseudomonas putida: receptor mapping with ferrichrome and its biomimetic analogs.

Authors:  E Jurkevitch; Y Hadar; Y Chen; J Libman; A Shanzer
Journal:  J Bacteriol       Date:  1992-01       Impact factor: 3.490
  2 in total

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