Literature DB >> 31961722

The Regulation of Mitochondrial Replacement Techniques Around the World.

I Glenn Cohen1, Eli Y Adashi2, Sara Gerke1, César Palacios-González3, Vardit Ravitsky4.   

Abstract

Mitochondrial replacement techniques (MRTs, also referred to as mitochondrial replacement therapies) have given hope to many women who wish to have genetically related children but have mitochondrial DNA mutations in their eggs. MRTs have also spurred deep ethical disagreements and led to different regulatory approaches worldwide. In this review, we discuss the current regulation of MRTs across several countries. After discussing the basics of the science, we describe the current law and policy directions in seven countries: the United Kingdom, the United States, Canada, Australia, Germany, Israel, and Singapore. We also discuss the emerging phenomenon of medical tourism (also called medical travel) for MRTs to places like Greece, Spain, Mexico, and Ukraine. We then pull out some key findings regarding similarities and differences in regulatory approaches around the world.

Entities:  

Keywords:  ethics; gene editing; law; mitochondrial replacement; mitochondrial transfer

Mesh:

Year:  2020        PMID: 31961722     DOI: 10.1146/annurev-genom-111119-101815

Source DB:  PubMed          Journal:  Annu Rev Genomics Hum Genet        ISSN: 1527-8204            Impact factor:   8.929


  6 in total

1.  Who will oversee the ethical limits of human embryo research?

Authors:  Eli Y Adashi; I Glenn Cohen
Journal:  Nat Biotechnol       Date:  2022-04       Impact factor: 54.908

2.  Gamete and embryo donation for research: what might shape the willingness to donate among gamete donors and recipients?

Authors:  Sandra Pinto da Silva; Cláudia de Freitas; Milton Severo; Susana Silva
Journal:  J Assist Reprod Genet       Date:  2022-08-20       Impact factor: 3.357

Review 3.  Disruptive Synergy: Melding of Human Genetics and Clinical Assisted Reproduction.

Authors:  Eli Y Adashi; I Glenn Cohen
Journal:  Cell Rep Med       Date:  2020-09-22

4.  Current progress in the therapeutic options for mitochondrial disorders.

Authors:  E Koňaříková; A Marković; Z Korandová; J Houštěk; T Mráček
Journal:  Physiol Res       Date:  2020-11-02       Impact factor: 1.881

5.  Responsible governance of human germline genome editing in China†.

Authors:  Yaojin Peng; Jianwei Lv; Lulu Ding; Xia Gong; Qi Zhou
Journal:  Biol Reprod       Date:  2022-07-25       Impact factor: 4.161

Review 6.  100 plus years of stem cell research-20 years of ISSCR.

Authors:  Urban Lendahl
Journal:  Stem Cell Reports       Date:  2022-06-14       Impact factor: 7.294

  6 in total

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