| Literature DB >> 3196163 |
Abstract
We examined whether the bone resorption induced by PGE2 was inhibited by SrCl2 using 45Ca-labelled calvaria of CD-strain mice in tissue culture. It was found that Sr salts inhibited physiological bone resorption in a dose-dependent manner (0.1-5.0 mM) and did not act via PGE2. Accordingly, it was suggested that Sr salts did not inhibit bone resorption induced by exogenous PGE2.Entities:
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Year: 1988 PMID: 3196163 DOI: 10.1007/bf00570150
Source DB: PubMed Journal: Arch Toxicol ISSN: 0340-5761 Impact factor: 5.153