| Literature DB >> 31960380 |
Abstract
The GOSemSim package, an R-based tool within the Bioconductor project, offers several methods based on information content and graph structure for measuring semantic similarity among GO terms, gene products and gene clusters. In this chapter, I illustrate the use of GOSemSim on a list of regulators in preimplantation embryos. A step-by-step analysis was provided as well as instructions on interpretation and visualization of the results. GOSemSim is open-source and is available from https://www.bioconductor.org/packages/GOSemSim .Keywords: Functional prediction; GOSemSim; Gene ontology; Reproducible research; Semantic similarity
Mesh：
Year: 2020 PMID： 31960380 DOI： 10.1007/978-1-0716-0301-7_11
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745