Luca Liberale1,2, Diana A Gorog3,4,5. 1. Center for Molecular Cardiology, University of Zurich, Schlieren, Switzerland. 2. First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy. 3. School of Life and Medical Sciences, Postgraduate Medical School, University of Hertfordshire, Hertfordshire, UK. 4. Department of Cardiology, East and North Hertfordshire NHS Trust, Hertfordshire, UK. 5. Faculty of Medicine, National Heart & Lung Institute, Imperial College, London, UK.