| Literature DB >> 31954835 |
Ganji Purnachandra Nagaraju1, Gowru Srivani2, Begum Dariya2, Gayathri Chalikonda3, Batoul Farran3, Santosh Kumar Behera4, Afroz Alam2, Mohammad Amjad Kamal5.
Abstract
Gastric cancer represents a deadly malignancy worldwide, yet current therapeutic regimens remain ineffective. Nanoparticle (NP) -based solutions could allow the design of novel therapeutic methods to eliminate this fatal disease. NPs typically carry out a significant role in multifunctional, multimodal imaging, and drug delivery carriers. In the recent decade, they have emerged as candidate approaches for the design of novel treatment strategies. Tumor nanotherapeutics characteristically possess various distinct advantages compared to conventional anti-cancer medications, which suffer from nonspecific bio-distribution, low solubility, and poor bioavailability. In this review, we will discuss the application of NPs in diagnosis and controlled drug delivery in gastric cancer (GC). We will focus on various NPs-based strategies employed against GC.Entities:
Keywords: Controlled drug delivery; Gastric cancer; Imaging; Nanoparticles; Nanotherapeutics
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Year: 2020 PMID: 31954835 DOI: 10.1016/j.semcancer.2020.01.006
Source DB: PubMed Journal: Semin Cancer Biol ISSN: 1044-579X Impact factor: 15.707