Literature DB >> 31953825

Using MetaboAnalyst 4.0 for Metabolomics Data Analysis, Interpretation, and Integration with Other Omics Data.

Jasmine Chong1, Jianguo Xia2,3,4,5.   

Abstract

MetaboAnalyst ( www.metaboanalyst.ca ) is an easy-to-use, comprehensive web-based tool, freely available for metabolomics data processing, statistical analysis, functional interpretation, as well as integration with other omics data. This chapter first provides an introductory overview to the current MetaboAnalyst (version 4.0) with regards to its underlying design concepts and user interface structure. Subsequent sections describe three common metabolomics data analysis workflows covering targeted metabolomics, untargeted metabolomics, and multi-omics data integration.

Keywords:  Enrichment analysis; Metabolic pathway analysis; Multi-omics integration; Multivariate statistics; Web server

Mesh：

Year:  2020        PMID： 31953825     DOI： 10.1007/978-1-0716-0239-3_17

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  45 in total

1.  Cognitive analysis of metabolomics data for systems biology.

Authors:  Erica L-W Majumder; Elizabeth M Billings; H Paul Benton; Richard L Martin; Amelia Palermo; Carlos Guijas; Markus M Rinschen; Xavier Domingo-Almenara; J Rafael Montenegro-Burke; Bradley A Tagtow; Robert S Plumb; Gary Siuzdak
Journal:  Nat Protoc       Date:  2021-01-22       Impact factor: 13.491

2.  Pathways and microbiome modifications related to surgery and enterocolitis in Hirschsprung disease.

Authors:  Roberto Biassoni; Eddi Di Marco; Stefano Avanzini; Alessio Pini Prato; Margherita Squillario; Elisabetta Ugolotti; Manuela Mosconi; Maria Grazia Faticato; Girolamo Mattioli
Journal:  Pediatr Surg Int       Date:  2021-10-22       Impact factor: 1.827

3.  Nuclear factor kappa-B contributes to cigarette smoke tolerance in pancreatic ductal adenocarcinoma through cysteine metabolism.

Authors:  Venugopal Gunda; Yashpal S Chhonker; Nagabhishek Sirpu Natesh; Pratima Raut; Sakthivel Muniyan; Todd A Wyatt; Daryl J Murry; Surinder K Batra; Satyanarayana Rachagani
Journal:  Biomed Pharmacother       Date:  2021-10-19       Impact factor: 6.529

4.  Untargeted metabolomics analysis identifies creatine, myo-inositol, and lipid pathway modulation in a murine model of tendinopathy.

Authors:  Katie J Sikes; Anna McConnell; Natalie Serkova; Brian Cole; David Frisbie
Journal:  J Orthop Res       Date:  2021-06-17       Impact factor: 3.494

5.  An integrative network analysis framework for identifying molecular functions in complex disorders examining major depressive disorder as a test case.

Authors:  Anup Mammen Oommen; Stephen Cunningham; Páraic S O'Súilleabháin; Brian M Hughes; Lokesh Joshi
Journal:  Sci Rep       Date:  2021-05-06       Impact factor: 4.379

6.  Identifying Phenotypically Distinct Fibroblast Subsets in Type 2 Diabetes-Associated Iatrogenic Laryngotracheal Stenosis.

Authors:  Ioan A Lina; Alexandra Berges; Rafael Ospino; Ruth J Davis; Kevin M Motz; Hsiu-Wen Tsai; Samuel Collins; Alexander T Hillel
Journal:  Otolaryngol Head Neck Surg       Date:  2021-06-15       Impact factor: 3.497

7.  Divergent metabolism between Trypanosoma congolense and Trypanosoma brucei results in differential sensitivity to metabolic inhibition.

Authors:  Pieter C Steketee; Emily A Dickie; James Iremonger; Kathryn Crouch; Edith Paxton; Siddharth Jayaraman; Omar A Alfituri; Georgina Awuah-Mensah; Ryan Ritchie; Achim Schnaufer; Tim Rowan; Harry P de Koning; Catarina Gadelha; Bill Wickstead; Michael P Barrett; Liam J Morrison
Journal:  PLoS Pathog       Date:  2021-07-26       Impact factor: 6.823

8.  Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19.

Authors:  Yamilé López-Hernández; Joel Monárrez-Espino; Ana-Sofía Herrera-van Oostdam; Julio Enrique Castañeda Delgado; Lun Zhang; Jiamin Zheng; Juan José Oropeza Valdez; Rupasri Mandal; Fátima de Lourdes Ochoa González; Juan Carlos Borrego Moreno; Flor M Trejo-Medinilla; Jesús Adrián López; José Antonio Enciso Moreno; David S Wishart
Journal:  Sci Rep       Date:  2021-07-19       Impact factor: 4.379

9.  Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathways.

Authors:  Yi Ding; Mariëlle C Haks; Gabriel Forn-Cuní; Junling He; Natalia Nowik; Amy C Harms; Thomas Hankemeier; Muhamed N H Eeza; Jörg Matysik; A Alia; Herman P Spaink
Journal:  Cell Biosci       Date:  2021-07-07       Impact factor: 7.133

10.  Untargeted fecal metabolome analysis in obese dogs after weight loss achieved by feeding a high-fiber-high-protein diet.

Authors:  Sandra Bermudez Sanchez; Rachel Pilla; Benjamin Sarawichitr; Alessandro Gramenzi; Fulvio Marsilio; Joerg M Steiner; Jonathan A Lidbury; Georgiana R T Woods; Jan S Suchodolski; Alexander J German
Journal:  Metabolomics       Date:  2021-07-06       Impact factor: 4.290
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