Literature DB >> 31951908

Acute stressors and clinical characteristics differentiate death by suicide, accident, or natural causes among illicit and prescription opiate users.

Alison J Athey1, Eleanor E Beale2, James C Overholser1, Craig A Stockmeier3, Courtney L Bagge4.   

Abstract

BACKGROUND: Opiate misuse has reached epidemic levels. Prevention efforts depend on distinguishing opiate users from abusers. The current study compared opioid users who died by natural cases, accidents, and suicide using psychological autopsy methods. Groups were compared on substance use characteristics, treatment history, experiences of negative life events, and circumstances at the time of death.
METHODS: Substance use and suicide risk were evaluated using psychological autopsy methods in 63 decedents with positive toxicology for opiates at death divided into three groups: adults dying by suicide (n = 19), accident (n = 19), and natural causes (n = 25). Groups were compared on several dependent measures, using chi-square analyses to examine categorical variables and one-way analyses of variance (ANOVA) to examine continuous variables.
RESULTS: Individuals who died by suicide were similar in many ways to adults who died by an accidental overdose. However, suicide completers were more likely to have struggled with severe depression, and previously attempted suicide, whereas the accidental overdose sample was more likely to display a chronic pattern of severe drug abuse.
CONCLUSIONS: The current study helps to distinguish between opiate users who are at risk for death by an accidental or intentional overdose. In the ongoing opiate crisis, clinicians must understand the risk of overdose and the nuances of accidental behaviors compared to purposeful ones. Signs of suicidal planning, relevant psychopathology, and ongoing life stress may be useful points of intervention for stopping the increasing number of deaths among opiate users.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Opiates; Overdose; Suicide

Mesh:

Substances:

Year:  2020        PMID: 31951908      PMCID: PMC7039758          DOI: 10.1016/j.drugalcdep.2020.107847

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  48 in total

1.  The next generation of psychological autopsy studies. Part I. Interview content.

Authors:  Kenneth R Conner; Annette L Beautrais; David A Brent; Yeates Conwell; Michael R Phillips; Barbara Schneider
Journal:  Suicide Life Threat Behav       Date:  2011-11-03

2.  A procedure that differentiates unintentional from intentional overdose in opioid abusers.

Authors:  Peter C Britton; Amy S B Bohnert; James D Wines; Kenneth R Conner
Journal:  Addict Behav       Date:  2011-09-02       Impact factor: 3.913

Review 3.  The psychological autopsy approach to studying suicide: a review of methodological issues.

Authors:  K Hawton; L Appleby; S Platt; T Foster; J Cooper; A Malmberg; S Simkin
Journal:  J Affect Disord       Date:  1998-09       Impact factor: 4.839

4.  Alcohol use to facilitate a suicide attempt: an event-based examination.

Authors:  Courtney L Bagge; Kenneth R Conner; Louren Reed; Milton Dawkins; Kevin Murray
Journal:  J Stud Alcohol Drugs       Date:  2015-05       Impact factor: 2.582

5.  National trends in long-term use of prescription opioids.

Authors:  Ramin Mojtabai
Journal:  Pharmacoepidemiol Drug Saf       Date:  2017-09-06       Impact factor: 2.890

6.  National trends in pharmaceutical opioid related overdose deaths compared to other substance related overdose deaths: 1999-2009.

Authors:  Susan Calcaterra; Jason Glanz; Ingrid A Binswanger
Journal:  Drug Alcohol Depend       Date:  2013-01-05       Impact factor: 4.492

7.  Characteristics of self-inflicted drug overdose deaths in North Carolina.

Authors:  Anna E Austin; Scott K Proescholdbell; Kathleen E Creppage; Alex Asbun
Journal:  Drug Alcohol Depend       Date:  2017-10-10       Impact factor: 4.492

8.  Assessment of depression and suicidal actions: agreement between suicide attempters and informant reports.

Authors:  Timothy M Dejong; James C Overholser
Journal:  Suicide Life Threat Behav       Date:  2009-02

9.  Depression and hopelessness as risk factors for suicide ideation, attempts and death: meta-analysis of longitudinal studies.

Authors:  Jessica D Ribeiro; Xieyining Huang; Kathryn R Fox; Joseph C Franklin
Journal:  Br J Psychiatry       Date:  2018-03-28       Impact factor: 9.319

10.  National record linkage study of mortality for a large cohort of opioid users ascertained by drug treatment or criminal justice sources in England, 2005-2009.

Authors:  Matthias Pierce; Sheila M Bird; Matthew Hickman; Tim Millar
Journal:  Drug Alcohol Depend       Date:  2014-11-18       Impact factor: 4.492

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.