Literature DB >> 31951580

HIV Latency: Stochastic across Multiple Scales.

Maike M K Hansen1, Benjamin Martin2, Leor S Weinberger3.   

Abstract

Proviral latency is a major barrier to a cure for HIV. In this issue of Cell Host & Microbe, Hataye et al. (2019) show that reactivation of HIV latency is a non-deterministic, highly stochastic (i.e., noisy) process and propose that stochastic transitions to exponential viral expansion require a critical threshold of virus.
Copyright © 2019 Elsevier Inc. All rights reserved.

Year:  2019        PMID: 31951580     DOI: 10.1016/j.chom.2019.11.010

Source DB:  PubMed          Journal:  Cell Host Microbe        ISSN: 1931-3128            Impact factor:   21.023


  1 in total

1.  A Two-Color Haploid Genetic Screen Identifies Novel Host Factors Involved in HIV-1 Latency.

Authors:  Mahsa Mollapour Sisakht; Enrico Ne; Panagiotis Moulos; Raquel Crespo; Michael Röling; Mateusz Stoszko; Elisa De Crignis; Helen Bodmer; Tsung Wai Kan; Maryam Akbarzadeh; Vaggelis Harokopos; Pantelis Hatzis; Robert-Jan Palstra; Tokameh Mahmoudi
Journal:  mBio       Date:  2021-12-07       Impact factor: 7.867

  1 in total

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