| Literature DB >> 31951542 |
Akira Nishio1, Barbara Rehermann2.
Abstract
Integrating transcriptomic, proteomic, and metabolomic data, Lercher et al. show in a mouse model of LCMV infection that type I interferon alters the expression and function of key enzymes of the urea cycle in hepatocytes. This results in altered systemic metabolism, attenuating antiviral T cell responses and ameliorating liver injury. Published by Elsevier Inc.Entities:
Mesh：
Substances：
Year: 2019 PMID： 31951542 DOI： 10.1016/j.immuni.2019.11.012
Source DB: PubMed Journal: Immunity ISSN： 1074-7613 Impact factor: 31.745