Literature DB >> 31951180

Lipid-based Nanoplatforms in Cancer Therapy: Recent Advances and Applications.

Kuldeep Rajpoot1.   

Abstract

Though modern available cancer therapies are effective, they possess major adverse effects, causing non-compliance to patients. Furthermore, the majority of the polymeric-based medication platforms are certainly not universally acceptable, due to their several restrictions. With this juxtaposition, lipid-based medication delivery systems have appeared as promising drug nanocarriers to replace the majority of the polymer-based products because they are in a position to reverse polymer as well as, drug-associated restrictions. Furthermore, the amalgamation of the basic principle of nanotechnology in designing lipid nanocarriers, which are the latest form of lipid carriers, has tremendous chemotherapeutic possibilities as tumor-targeted drug-delivery pertaining to tumor therapy. Apart from this, it is reported that nearly 40% of the modern medication entities are lipophilic. Moreover, research continues to be efficient in attaining a significant understanding of the absorption and bioavailability of the developed lipids systems. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  Cancer; lipids systems; liposomes; nanocarriers; solid lipid nanoparticles; targeted delivery.

Year:  2020        PMID: 31951180     DOI: 10.2174/1568009620666200115160805

Source DB:  PubMed          Journal:  Curr Cancer Drug Targets        ISSN: 1568-0096            Impact factor:   3.428


  1 in total

1.  pH-Responsive PEGylated Niosomal Nanoparticles as an Active-Targeting Cyclophosphamide Delivery System for Gastric Cancer Therapy.

Authors:  Farnaz Khodabakhsh; Mahsa Bourbour; Mohammad Tavakkoli Yaraki; Saina Bazzazan; Haleh Bakhshandeh; Reza Ahangari Cohan; Yen Nee Tan
Journal:  Molecules       Date:  2022-08-24       Impact factor: 4.927

  1 in total

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