| Literature DB >> 31950016 |
Kunihisa Nezu1, Hiromichi Katayama1, Atsushi Kyan1.
Abstract
A combination therapy of nivolumab and ipilimumab is effective for advanced renal cell carcinoma, but there are concerns about immune-related adverse events. A 46-year-old man was hospitalized for metastatic renal cell carcinoma. On day 9, he received nivolumab and ipilimumab. On days 16 and 49, he presented with fever, skin rash, and hypotension after contrast-enhanced computed tomography. A 70-year-old man was hospitalized for metastatic renal cell carcinoma. On day 9, he received nivolumab and ipilimumab. On day 44, he presented with fever, skin rash, and hypotension after contrast-enhanced computed tomography. Both patients were diagnosed with anaphylaxis due to the contrast agent. © The Japan Society of Clinical Oncology 2019.Entities:
Keywords: Anaphylaxis; Contrast agent allergy; Immune-related adverse event; Ipilimumab; Nivolumab; Renal cell carcinoma
Year: 2019 PMID: 31950016 PMCID: PMC6942556 DOI: 10.1007/s13691-019-00388-0
Source DB: PubMed Journal: Int Cancer Conf J ISSN: 2192-3183