Literature DB >> 3194849

Not all "occult" papillary carcinomas are "minimal".

M D Allo1, W Christianson, D Koivunen.   

Abstract

"Occult" papillary carcinomas are characterized as small papillary tumors of less than 1.5 cm in maximum diameter, with or without bulky metastatic deposits in cervical nodes. The primary lesion is usually not palpable, and although the clinical behavior usually follows a benign course, tumors with unfavorable histologic features (invasiveness, multifocality) or extrathyroidal disease or a combination of both may not do so. In this report six cases are presented to illustrate this entity. No patient had a history of irradiation to the head or neck. All had primary lesions smaller than 1.5 cm. None had a palpable nodule or abnormal thyroid scan results, and the diagnosis of thyroid cancer was based on cervical lymph node or lung biopsy specimens, which revealed papillary thyroid cancer. All of the patients underwent total or near-total thyroidectomies and were found to have small, invasive papillary lesions with additional metastases to cervical nodes noted at the time of thyroidectomy. Adjunctive treatment consisted of a 5 mCi iodine-131 scan, ablative iodine-131 therapy, and suppression with L-thyroxine. Although distant metastasis to lung or other organs is uncommon and the mortality rate is low (as in larger papillary cancers), these invasive lesions--despite their small size--have a high propensity for recurrence and should be considered to behave more like encapsulated papillary tumors with extrathyroidal extension than like their small, unencapsulated intrathyroidal counterparts.

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Year:  1988        PMID: 3194849

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  10 in total

1.  Occult papillary microcarcinoma of the thyroid--a potential pitfall of fine needle aspiration cytology?

Authors:  H R Harach; E Saravia Day; S B Zusman
Journal:  J Clin Pathol       Date:  1991-03       Impact factor: 3.411

2.  Papillary microcarcinoma: is there any difference between clinically overt and occult tumors?

Authors:  Chung-Yau Lo; Wai-Fan Chan; Brian Hung-Hin Lang; King-Yin Lam; Koon-Yat Wan
Journal:  World J Surg       Date:  2006-05       Impact factor: 3.352

3.  Ectopic thyroid follicles in the submucosa of the duodenum.

Authors:  T Takahashi; H Ishikura; H Kato; T Tanabe; T Yoshiki
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1991

4.  Papillary thyroid microcarcinoma: incidence and prognostic factors.

Authors:  Sophie Jacquot-Laperrière; Andrei P Timoshenko; Jean-Marc Dumollard; Michel Peoc'h; Bruno Estour; Christian Martin; Jean-Michel Prades
Journal:  Eur Arch Otorhinolaryngol       Date:  2007-04-13       Impact factor: 2.503

5.  Papillary thyroid microcarcinoma: extrathyroidal extension, lymph node metastases, and risk factors for recurrence in a high prevalence of goiter area.

Authors:  Celestino P Lombardi; Rocco Bellantone; Carmela De Crea; Nunzia C Paladino; Guido Fadda; Massimo Salvatori; Marco Raffaelli
Journal:  World J Surg       Date:  2010-06       Impact factor: 3.352

6.  Three distinctly different kinds of papillary thyroid microcarcinoma should be recognized: our treatment strategies and outcomes.

Authors:  Iwao Sugitani; Kazuhisa Toda; Keiko Yamada; Noriko Yamamoto; Motoko Ikenaga; Yoshihide Fujimoto
Journal:  World J Surg       Date:  2010-06       Impact factor: 3.352

7.  Incidental papillary microcarcinoma of the thyroid--factors affecting lymph node metastasis.

Authors:  Kaptan Gülben; Uğur Berberoğlu; Orhan Celen; Hüsnü H Mersin
Journal:  Langenbecks Arch Surg       Date:  2007-08-10       Impact factor: 3.445

8.  Natural History of Asymptomatic Papillary Thyroid Microcarcinoma: Time-Dependent Changes in Calcification and Vascularity During Active Surveillance.

Authors:  Osamu Fukuoka; Iwao Sugitani; Aya Ebina; Kazuhisa Toda; Kazuyoshi Kawabata; Keiko Yamada
Journal:  World J Surg       Date:  2016-03       Impact factor: 3.352

9.  Papillary microcarcinomas of the thyroid gland and immunohistochemical analysis of expression of p53 protein in papillary microcarcinomas.

Authors:  Demet Corapcioglu; Serpil D Sak; Tuncay Delibasi; Vedia Tonyukuk; Nuri Kamel; Ali R Uysal; Savas Kocak; Semih Aydintug; Gurbuz Erdogan
Journal:  J Transl Med       Date:  2006-07-05       Impact factor: 5.531

10.  Cervical masses as manifestation of papillary thyroid carcinomas </=10 mm in diameter, in patients with unknown thyroid disease.

Authors:  Kalliopi Pazaitou-Panayiotou; Maria Alevizaki; Maria Boudina; Apostolos Drimonitis; Anastasia Kiziridou; Iraklis Vainas
Journal:  Thyroid Res       Date:  2008-12-06
  10 in total

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