| Literature DB >> 31946512 |
Yuru Song, Helen Kemprecos, Jing Wang, Zhe Chen.
Abstract
Pain is a complex multidimensional experience, and pain perception is still incompletely understood. Here we combine animal behavior, electrophysiology, and computer modeling to dissect mechanisms of evoked and spontaneous pain. We record the local field potentials (LFPs) from the primary somatosensory cortex (S1) and anterior cingulate cortex (ACC) of freely behaving rats during pain episodes, and develop a predictive coding model to investigate the temporal coordination of oscillatory activity between the S1 and ACC. Our preliminary results from computational simulations support the experimental findings and provide new predictions.Entities:
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Year: 2019 PMID： 31946512 PMCID： PMC8025043 DOI： 10.1109/EMBC.2019.8857298
Source DB: PubMed Journal: Annu Int Conf IEEE Eng Med Biol Soc ISSN： 2375-7477