Literature DB >> 31938864

Performance of a rapid two-sequence screening protocol for osteomyelitis of the foot.

Adam D Singer1, Monica Umpierrez2, Aparna Kakarala2, Marcos C Schechter3, Michael Maceroli4, Gulshan B Sharma5, Ravi R Rajani6.   

Abstract

OBJECTIVE: Compare a two sequence protocol to a standard protocol in the detection of pedal osteomyelitis (OM) and abscesses and to identify patients that benefit from a full protocol.
MATERIALS AND METHODS: One hundred thirty-two foot MRIs ordered to assess for OM were enrolled, and the following items were extracted from the clinical reports: use of IV contrast, the presence of OM, reactive osteitis, and a soft tissue abscess. Using only one T1 nonfat-suppressed and one fluid sensitive fat-suppressed sequences, two experienced musculoskeletal radiologists reviewed each case for the presence of OM, reactive osteitis, or an abscess. A Kappa test was calculated to assess for interobserver agreement, and diagnostic performance was determined. The McNemar test was used to assess for the effect of contrast.
RESULTS: Agreement between both observers and the clinical report on the presence of osteomyelitis was substantial ( k = 0.63 and 0.72, p < 0.001), while the agreement for abscess was fair (k = 0.29 and 0.38, p < 0.001). For osteomyelitis, both observers showed good accuracy (0.85 and 0.86). When screening bone for a normal versus abnormal case, this method was highly sensitive (0.97-0.98), but was less sensitive for abscess (0.63-0.75). Fifty-one percent of exams used contrast, and it did impact the diagnosis of abscess for one observer.
CONCLUSION: This rapid protocol is accurate in making the diagnosis of OM, and its high sensitivity makes it useful to screen for patients that would benefit from a full protocol.

Entities:  

Keywords:  Foot; MRI; Osteomyelitis; Pedal; Screening

Mesh:

Substances:

Year:  2020        PMID: 31938864     DOI: 10.1007/s00256-019-03367-x

Source DB:  PubMed          Journal:  Skeletal Radiol        ISSN: 0364-2348            Impact factor:   2.199


  24 in total

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Review 4.  Diabetic Foot Ulcers and Their Recurrence.

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5.  Abbreviated MRI of the foot in patients with suspected osteomyelitis.

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6.  Medical Imaging and Laboratory Analysis of Diagnostic Accuracy in 107 Consecutive Hospitalized Patients With Diabetic Foot Osteomyelitis and Partial Foot Amputations.

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7.  Outcomes in diabetic foot ulcer patients with isolated T2 marrow signal abnormality in the underlying bone: should the diagnosis of "osteitis" be changed to "early osteomyelitis"?

Authors:  Dennis Duryea; Stephanie Bernard; Donald Flemming; Eric Walker; Cristy French
Journal:  Skeletal Radiol       Date:  2017-05-11       Impact factor: 2.199

8.  Statistical reliability of bone biopsy for the diagnosis of diabetic foot osteomyelitis.

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9.  Diagnostic accuracy of various modalities relative to open bone biopsy for detection of long bone posttraumatic osteomyelitis.

Authors:  Vivek Chadayammuri; Benoit Herbert; Jiandong Hao; Andreas Mavrogenis; Juan C Quispe; Ji Wan Kim; Heather Young; Mark Hake; Cyril Mauffrey
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10.  Level of Agreement With a Multi-Test Approach to the Diagnosis of Diabetic Foot Osteomyelitis.

Authors:  Andrew J Meyr; Kyung Seo; Jasvir S Khurana; Rachana Choksi; Baidarbhi Chakraborty
Journal:  J Foot Ankle Surg       Date:  2018-09-01       Impact factor: 1.286

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