| Literature DB >> 3192920 |
G Pastore1, T Santantonio, L Monno, M Milella, N Luchena, G Angarano.
Abstract
A case of HIV superinfection observed in an HBsAg/HBeAg-positive male homosexual with chronic persistent hepatitis is described. Soon after the appearance of clinical and serological features of acute HIV infection, a rapid fall to a normal value of ALT was noted with simultaneous recrudescence of HBV replication lasting for several months as detected by an increase of the HBV-DNA concentration in the serum. Our observations suggest that the reduction of hepatocyte necrosis and the increase in HBV replication were a consequence of impaired T cell function during acute HIV infection.Entities:
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Year: 1988 PMID: 3192920 DOI: 10.1016/s0168-8278(88)80478-1
Source DB: PubMed Journal: J Hepatol ISSN: 0168-8278 Impact factor: 25.083