Dax G Rumsey1, Ronald M Laxer2. 1. Department of Pediatrics, Division of Rheumatology, University of Alberta, 3-502 ECHA, 11405 87 Avenue NW, Edmonton, AB, T6G 1C9, Canada. Rumsey@ualberta.ca. 2. Departments of Paediatrics and Medicine, Division of Rheumatology, University of Toronto and The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada.
Abstract
PURPOSE OF REVIEW: Childhood arthritis is in need of a new system of classification, owing to deficiencies in the International League of Associations for Rheumatology (ILAR) criteria. We briefly review the history of classification of childhood arthritis, discuss the major criticisms of the current system, and highlight current initiatives to address those concerns. RECENT FINDINGS: Recent studies in both pediatric and adult rheumatology into the biologic basis of disease as well as the clinical patterns of presentation have informed the efforts toward developing a new classification system. Several efforts are currently underway to improve the classification of childhood arthritis, most notably the project of the Pediatric Rheumatology International Trials Organization (PRINTO). This international alliance of pediatric rheumatologists has begun a 4-step process to create new classification criteria for childhood arthritis. They are currently on step 3 of the process.
PURPOSE OF REVIEW: Childhood arthritis is in need of a new system of classification, owing to deficiencies in the International League of Associations for Rheumatology (ILAR) criteria. We briefly review the history of classification of childhood arthritis, discuss the major criticisms of the current system, and highlight current initiatives to address those concerns. RECENT FINDINGS: Recent studies in both pediatric and adult rheumatology into the biologic basis of disease as well as the clinical patterns of presentation have informed the efforts toward developing a new classification system. Several efforts are currently underway to improve the classification of childhood arthritis, most notably the project of the Pediatric Rheumatology International Trials Organization (PRINTO). This international alliance of pediatric rheumatologists has begun a 4-step process to create new classification criteria for childhood arthritis. They are currently on step 3 of the process.
Authors: Ross E Petty; Taunton R Southwood; Prudence Manners; John Baum; David N Glass; Jose Goldenberg; Xiaohu He; Jose Maldonado-Cocco; Javier Orozco-Alcala; Anne-Marie Prieur; Maria E Suarez-Almazor; Patricia Woo Journal: J Rheumatol Date: 2004-02 Impact factor: 4.666
Authors: Sampath Prahalad; Susan D Thompson; Karen N Conneely; Yunxuan Jiang; Traci Leong; Jennifer Prozonic; Milton R Brown; Lori A Ponder; Sheila T Angeles-Han; Larry B Vogler; Christine Kennedy; Carol A Wallace; Carol A Wise; Marilynn Punaro; Ann Reed; Jane L Park; Elizabeth D Mellins; Andrew S Zeft; John F Bohnsack; David N Glass Journal: Arthritis Rheum Date: 2012-03
Authors: E J Brewer; J Bass; J Baum; J T Cassidy; C Fink; J Jacobs; V Hanson; J E Levinson; J Schaller; J S Stillman Journal: Arthritis Rheum Date: 1977-03
Authors: Jill A Hollenbach; Susan D Thompson; Teodorica L Bugawan; Mary Ryan; Marc Sudman; Miranda Marion; Carl D Langefeld; Glenys Thomson; Henry A Erlich; David N Glass Journal: Arthritis Rheum Date: 2010-06
Authors: Alberto Martini; Angelo Ravelli; Tadej Avcin; Michael W Beresford; Ruben Burgos-Vargas; Ruben Cuttica; Norman T Ilowite; Raju Khubchandani; Ronald M Laxer; Daniel J Lovell; Ross E Petty; Carol A Wallace; Nico M Wulffraat; Angela Pistorio; Nicolino Ruperto Journal: J Rheumatol Date: 2018-10-01 Impact factor: 4.666
Authors: J Sieper; D van der Heijde; R Landewé; J Brandt; R Burgos-Vagas; E Collantes-Estevez; B Dijkmans; M Dougados; M A Khan; M Leirisalo-Repo; S van der Linden; W P Maksymowych; H Mielants; I Olivieri; M Rudwaleit Journal: Ann Rheum Dis Date: 2009-01-15 Impact factor: 19.103
Authors: Anne Hinks; Joanna Cobb; Miranda C Marion; Sampath Prahalad; Marc Sudman; John Bowes; Paul Martin; Mary E Comeau; Satria Sajuthi; Robert Andrews; Milton Brown; Wei-Min Chen; Patrick Concannon; Panos Deloukas; Sarah Edkins; Stephen Eyre; Patrick M Gaffney; Stephen L Guthery; Joel M Guthridge; Sarah E Hunt; Judith A James; Mehdi Keddache; Kathy L Moser; Peter A Nigrovic; Suna Onengut-Gumuscu; Mitchell L Onslow; Carlos D Rosé; Stephen S Rich; Kathryn J A Steel; Edward K Wakeland; Carol A Wallace; Lucy R Wedderburn; Patricia Woo; John F Bohnsack; Johannes Peter Haas; David N Glass; Carl D Langefeld; Wendy Thomson; Susan D Thompson Journal: Nat Genet Date: 2013-04-21 Impact factor: 38.330
Authors: Peter A Nigrovic; Robert A Colbert; V Michael Holers; Seza Ozen; Nicolino Ruperto; Susan D Thompson; Lucy R Wedderburn; Rae S M Yeung; Alberto Martini Journal: Nat Rev Rheumatol Date: 2021-03-17 Impact factor: 20.543