| Literature DB >> 3192752 |
A M McBain1, I R Brown, D G Menzies, I W Campbell.
Abstract
Poorly controlled type II diabetic patients with hypomagnesaemia, hypermagnesuria, and hypercalciuria were allocated to treatment with either metformin or glipizide, to determine the effects on some indices of mineral metabolism. Despite comparable improvement in glycaemic control, assessed by glucose and haemoglobin A1, there were significant differences between the two groups in the handling of magnesium. Patients receiving metformin showed a reduction in magnesium excretion but remained hypomagnesaemic and hypercalciuric. In contrast, patients receiving glipizide exhibited little change in either magnesium or calcium excretion but showed a significant rise in serum magnesium.Entities:
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Year: 1988 PMID： 3192752 PMCID： PMC1141646 DOI： 10.1136/jcp.41.9.933
Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411