Literature DB >> 31924487

Prescribing and Consumption of Opioids After Primary, Unilateral Total Hip and Knee Arthroplasty in Opioid-Naive Patients.

Karl C Roberts1, Stephanie E Moser2, Angela C Collins3, Brian R McCardel4, Kyle A Schultz5, Nathaniel E Schaffer6, Joseph S Tramer7, Creg A Carpenter8, Jennifer M Pierce2, Alan Edwards1, Kendall M Dubois2, Chad M Brummett2.   

Abstract

BACKGROUND: This cohort study was designed to determine the discrepancy between the quantity of opioid prescribed vs that which was consumed after total knee arthroplasty (TKA) and total hip arthroplasty (THA) in opioid-naive patients.
METHODS: Seven hundred twenty-three opioid-naive patients (426 TKAs and 297 THAs) from 7 hospitals in Michigan were contacted within 3 months of their surgery. Opioid prescribing and self-reported consumption was calculated in oral morphine equivalents (OMEs). Secondary outcomes included opioid refill in the first 90 days, pain in the first 7 days post-operatively, and satisfaction with pain care.
RESULTS: For TKA, the mean prescribing was 632 mg OME (±229), and the mean consumption was 416 mg (±279). For THA, the mean prescribing was 584 mg OME (±335), and the mean consumption was 285 mg (±301). There were no associations between the amount of opioid prescribed and the likelihood of refill, post-operative pain, or satisfaction with pain control. The amount of opioid prescribed was associated with increased consumption, such that each increase of 1 pill was associated with approximately an additional half pill consumed after adjusting for other covariates. Moreover, 48.2% felt that they received "More" or "Much more" opioid than they needed.
CONCLUSION: We recommend no more than 50 tablets of 5 mg oxycodone or its equivalent after TKA and 30 tablets after THA. Although dose reductions in other surgeries have not resulted in harm, continued assessment is needed to ensure that there are no unintended effects of opioid reduction, including worsened pain, decreased satisfaction, emergency department visits, or hospital readmissions. LEVEL OF EVIDENCE: Level III; Retrospective, cohort study.
Copyright © 2019. Published by Elsevier Inc.

Entities:  

Keywords:  arthroplasty; hip; knee; opioid; pain

Mesh:

Substances:

Year:  2019        PMID: 31924487     DOI: 10.1016/j.arth.2019.08.036

Source DB:  PubMed          Journal:  J Arthroplasty        ISSN: 0883-5403            Impact factor:   4.757


  7 in total

1.  Prescription and Prescriber Specialty Characteristics of Initial Opioid Prescriptions Associated with Chronic Use.

Authors:  Scott G Weiner; Shih-Chuan Chou; Cindy Y Chang; Chad Garner; Sanae El Ibrahimi; Sara Hallvik; Michelle Hendricks; Olesya Baker
Journal:  Pain Med       Date:  2020-12-25       Impact factor: 3.750

2.  To be mindful of the breath or pain: Comparing two brief preoperative mindfulness techniques for total joint arthroplasty patients.

Authors:  Adam W Hanley; Jeremy Gililland; Eric L Garland
Journal:  J Consult Clin Psychol       Date:  2021-06-24

3.  Postdischarge Opioid Use after Total Hip and Total Knee Arthroplasty.

Authors:  Keenan Atwood; Taylor Shackleford; Wesley Lemons; Jennifer L Eicher; Brock A Lindsey; Adam E Klein
Journal:  Arthroplast Today       Date:  2021-01-30

4.  Patients Use Fewer Opioids Than Prescribed After Arthroscopic Release of Elbow Contracture: An Evidence-Based Opioid Prescribing Guideline to Reduce Excess.

Authors:  Jorge Rojas Lievano; Dani Rotman; Maegan N Shields; Mark E Morrey; Joaquin Sanchez-Sotelo; Dave R Shukla; Tammy S Olson; Anthony M Vaichinger; James S Fitzsimmons; Shawn W O'Driscoll
Journal:  Arthrosc Sports Med Rehabil       Date:  2021-11-17

5.  Socioeconomic status and use of analgesic drugs before and after primary hip arthroplasty: a population-based cohort study of 103,209 patients during 1996-2018.

Authors:  André N Klenø; Martin B Stisen; Nina M Edwards; Inger Mechlenburg; Alma B Pedersen
Journal:  Acta Orthop       Date:  2022-01-03       Impact factor: 3.717

6.  Narcotic Refills and Patient Satisfaction With Pain Control After Total Joint Arthroplasty.

Authors:  Jeffrey B Stambough; Ryan Hui; Eric R Siegel; Paul K Edwards; C Lowry Barnes; Simon C Mears
Journal:  J Arthroplasty       Date:  2020-08-04       Impact factor: 4.757

7.  A meta-analysis on advantages of peripheral nerve block post-total knee arthroplasty.

Authors:  Di You; Lu Qin; Kai Li; Di Li; Guoqing Zhao; Longyun Li
Journal:  Korean J Pain       Date:  2021-07-01
  7 in total

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