| Literature DB >> 31924114 |
Zizhong Liu1, Gui Luo2, Ruikai Du1, Weijia Sun1, Jianwei Li1, Haiyun Lan3, Pu Chen3, Xinxin Yuan1, Dengchao Cao1, Yuheng Li1, Caizhi Liu1, Shuai Liang1, Xiaoyan Jin1, Ruifu Yang4, Yujing Bi4, Yanping Han4, Ping Cao3, Wei Zhao3, Shukuan Ling1, Yingxian Li1.
Abstract
Interaction between humans and the gut microbiota is important for human physiology. Here, the gut microbiota was analyzed via metagenomic sequencing, and the fluctuations in the gut microbiota under the conditions of spaceflight were characterized. The composition and function of the gut microbiota were substantially affected by spaceflight; however, individual specificity was uncompromised. We further confirmed the species fluctuations and functional genes from both missions. Resistance and virulence genes in the gut microbiota were affected by spaceflight, but the species attributions remained stable. Spaceflight markedly affected the composition and function of the human gut microbiota, implying that the human gut microbiota is sensitive to spaceflight.Entities:
Keywords: Gut microbiota; resistance genes; spaceflight; species composition; virulence genes
Year: 2020 PMID： 31924114 PMCID： PMC7524348 DOI： 10.1080/19490976.2019.1710091
Source DB: PubMed Journal: Gut Microbes ISSN： 1949-0976