Literature DB >> 31922891

Structure-function relationship of the slow delayed rectifier channel: impactful questions in 2020 and beyond.

Gea-Ny Tseng1.   

Abstract

Keywords:  KCNE1; KCNQ1; LQT; structure-function relationship

Mesh：

Substances：

Year:  2020        PMID： 31922891      PMCID： PMC7199241          DOI： 10.1152/ajpheart.00009.2020

Source DB:  PubMed          Journal:  Am J Physiol Heart Circ Physiol        ISSN： 0363-6135            Impact factor:   4.733


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  10 in total

1.  Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2.

Authors:  Min Jiang; Xulin Xu; Yuhong Wang; Futoshi Toyoda; Xian-Sheng Liu; Mei Zhang; Richard B Robinson; Gea-Ny Tseng
Journal:  J Biol Chem       Date:  2009-04-16       Impact factor: 5.157

2.  Building KCNQ1/KCNE1 channel models and probing their interactions by molecular-dynamics simulations.

Authors:  Yu Xu; Yuhong Wang; Xuan-Yu Meng; Mei Zhang; Min Jiang; Meng Cui; Gea-Ny Tseng
Journal:  Biophys J       Date:  2013-12-03       Impact factor: 4.033

3.  Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed.

Authors:  Min Jiang; Yuhong Wang; Gea-Ny Tseng
Journal:  Circ Arrhythm Electrophysiol       Date:  2017-06

4.  Physical and functional interaction sites in cytoplasmic domains of KCNQ1 and KCNE1 channel subunits.

Authors:  Jerri Chen; Zhenning Liu; John Creagh; Renjian Zheng; Thomas V McDonald
Journal:  Am J Physiol Heart Circ Physiol       Date:  2019-12-13       Impact factor: 4.733

Review 5.  Beyond the One Gene-One Disease Paradigm: Complex Genetics and Pleiotropy in Inheritable Cardiac Disorders

Authors:  Marina Cerrone; Carol Ann Remme; Rafik Tadros; Connie R Bezzina; Mario Delmar
Journal:  Circulation       Date:  2019-08-12       Impact factor: 29.690

6.  Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

Authors:  Norbert Jost; László Virág; Miklós Bitay; János Takács; Csaba Lengyel; Péter Biliczki; Zsolt Nagy; Gábor Bogáts; David A Lathrop; Julius G Papp; András Varró
Journal:  Circulation       Date:  2005-08-29       Impact factor: 29.690

7.  The KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interaction.

Authors:  Reuven Wiener; Yoni Haitin; Liora Shamgar; M Carmen Fernández-Alonso; Ariadna Martos; Orna Chomsky-Hecht; Germán Rivas; Bernard Attali; Joel A Hirsch
Journal:  J Biol Chem       Date:  2007-12-29       Impact factor: 5.157

8.  Structure of KCNE1 and implications for how it modulates the KCNQ1 potassium channel.

Authors:  Congbao Kang; Changlin Tian; Frank D Sönnichsen; Jarrod A Smith; Jens Meiler; Alfred L George; Carlos G Vanoye; Hak Jun Kim; Charles R Sanders
Journal:  Biochemistry       Date:  2008-07-09       Impact factor: 3.162

9.  Cryo-EM Structure of a KCNQ1/CaM Complex Reveals Insights into Congenital Long QT Syndrome.

Authors:  Ji Sun; Roderick MacKinnon
Journal:  Cell       Date:  2017-06-01       Impact factor: 41.582

10.  Protein structure aids predicting functional perturbation of missense variants in SCN5A and KCNQ1.

Authors:  Brett M Kroncke; Jeffrey Mendenhall; Derek K Smith; Charles R Sanders; John A Capra; Alfred L George; Jeffrey D Blume; Jens Meiler; Dan M Roden
Journal:  Comput Struct Biotechnol J       Date:  2019-02-01       Impact factor: 7.271
  10 in total

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