Literature DB >> 31922671

Transcriptome-wide association analysis offers novel opportunities for clinical translation of genetic discoveries on mental disorders.

Eske M Derks1, Eric R Gamazon2,3,4,5.   

Abstract

Entities:  

Year:  2020        PMID: 31922671      PMCID: PMC6953546          DOI: 10.1002/wps.20702

Source DB:  PubMed          Journal:  World Psychiatry        ISSN: 1723-8617            Impact factor:   49.548


× No keyword cloud information.
  9 in total

1.  The support of human genetic evidence for approved drug indications.

Authors:  Matthew R Nelson; Hannah Tipney; Jeffery L Painter; Judong Shen; Paola Nicoletti; Yufeng Shen; Aris Floratos; Pak Chung Sham; Mulin Jun Li; Junwen Wang; Lon R Cardon; John C Whittaker; Philippe Sanseau
Journal:  Nat Genet       Date:  2015-06-29       Impact factor: 38.330

2.  Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry.

Authors:  Hon-Cheong So; Carlos Kwan-Long Chau; Wan-To Chiu; Kin-Sang Ho; Cho-Pong Lo; Stephanie Ho-Yue Yim; Pak-Chung Sham
Journal:  Nat Neurosci       Date:  2017-08-14       Impact factor: 24.884

3.  The promise and challenges of drug repurposing in psychiatry.

Authors:  Maurizio Fava
Journal:  World Psychiatry       Date:  2018-02       Impact factor: 49.548

4.  Multi-tissue transcriptome analyses identify genetic mechanisms underlying neuropsychiatric traits.

Authors:  Eric R Gamazon; Aeilko H Zwinderman; Nancy J Cox; Damiaan Denys; Eske M Derks
Journal:  Nat Genet       Date:  2019-05-13       Impact factor: 38.330

5.  Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.

Authors:  David M Howard; Mark J Adams; Toni-Kim Clarke; Jonathan D Hafferty; Jude Gibson; Masoud Shirali; Jonathan R I Coleman; Saskia P Hagenaars; Joey Ward; Eleanor M Wigmore; Clara Alloza; Xueyi Shen; Miruna C Barbu; Eileen Y Xu; Heather C Whalley; Riccardo E Marioni; David J Porteous; Gail Davies; Ian J Deary; Gibran Hemani; Klaus Berger; Henning Teismann; Rajesh Rawal; Volker Arolt; Bernhard T Baune; Udo Dannlowski; Katharina Domschke; Chao Tian; David A Hinds; Maciej Trzaskowski; Enda M Byrne; Stephan Ripke; Daniel J Smith; Patrick F Sullivan; Naomi R Wray; Gerome Breen; Cathryn M Lewis; Andrew M McIntosh
Journal:  Nat Neurosci       Date:  2019-02-04       Impact factor: 28.771

6.  Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

Authors:  Antonio F Pardiñas; Peter Holmans; Andrew J Pocklington; Valentina Escott-Price; Stephan Ripke; Noa Carrera; Sophie E Legge; Sophie Bishop; Darren Cameron; Marian L Hamshere; Jun Han; Leon Hubbard; Amy Lynham; Kiran Mantripragada; Elliott Rees; James H MacCabe; Steven A McCarroll; Bernhard T Baune; Gerome Breen; Enda M Byrne; Udo Dannlowski; Thalia C Eley; Caroline Hayward; Nicholas G Martin; Andrew M McIntosh; Robert Plomin; David J Porteous; Naomi R Wray; Armando Caballero; Daniel H Geschwind; Laura M Huckins; Douglas M Ruderfer; Enrique Santiago; Pamela Sklar; Eli A Stahl; Hyejung Won; Esben Agerbo; Thomas D Als; Ole A Andreassen; Marie Bækvad-Hansen; Preben Bo Mortensen; Carsten Bøcker Pedersen; Anders D Børglum; Jonas Bybjerg-Grauholm; Srdjan Djurovic; Naser Durmishi; Marianne Giørtz Pedersen; Vera Golimbet; Jakob Grove; David M Hougaard; Manuel Mattheisen; Espen Molden; Ole Mors; Merete Nordentoft; Milica Pejovic-Milovancevic; Engilbert Sigurdsson; Teimuraz Silagadze; Christine Søholm Hansen; Kari Stefansson; Hreinn Stefansson; Stacy Steinberg; Sarah Tosato; Thomas Werge; David A Collier; Dan Rujescu; George Kirov; Michael J Owen; Michael C O'Donovan; James T R Walters
Journal:  Nat Genet       Date:  2018-02-26       Impact factor: 38.330

7.  A gene-based association method for mapping traits using reference transcriptome data.

Authors:  Eric R Gamazon; Heather E Wheeler; Kaanan P Shah; Sahar V Mozaffari; Keston Aquino-Michaels; Robert J Carroll; Anne E Eyler; Joshua C Denny; Dan L Nicolae; Nancy J Cox; Hae Kyung Im
Journal:  Nat Genet       Date:  2015-08-10       Impact factor: 38.330

8.  Genetic effects on gene expression across human tissues.

Authors:  Alexis Battle; Christopher D Brown; Barbara E Engelhardt; Stephen B Montgomery
Journal:  Nature       Date:  2017-10-11       Impact factor: 49.962

9.  Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.

Authors:  Eric R Gamazon; Ayellet V Segrè; Martijn van de Bunt; Xiaoquan Wen; Hualin S Xi; Farhad Hormozdiari; Halit Ongen; Anuar Konkashbaev; Eske M Derks; François Aguet; Jie Quan; Dan L Nicolae; Eleazar Eskin; Manolis Kellis; Gad Getz; Mark I McCarthy; Emmanouil T Dermitzakis; Nancy J Cox; Kristin G Ardlie
Journal:  Nat Genet       Date:  2018-06-28       Impact factor: 38.330

  9 in total
  1 in total

1.  Identifying and Exploring the Candidate Susceptibility Genes of Cirrhosis Using the Multi-Tissue Transcriptome-Wide Association Study.

Authors:  Xiao-Bo Zhu; Yu-Qing Hou; Xiang-Yu Ye; Yi-Xin Zou; Xue-Shan Xia; Sheng Yang; Peng Huang; Rong-Bin Yu
Journal:  Front Genet       Date:  2022-05-13       Impact factor: 4.772

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.