Literature DB >> 31922664

The synaptic pruning hypothesis of schizophrenia: promises and challenges.

Matcheri Keshavan1, Paulo Lizano1, Konasale Prasad2,3,4.   

Abstract

Entities:  

Year:  2020        PMID： 31922664      PMCID： PMC6953570          DOI： 10.1002/wps.20725

Source DB:  PubMed          Journal:  World Psychiatry        ISSN： 1723-8617            Impact factor:   49.548


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  8 in total

1.  Alterations in brain high-energy phosphate and membrane phospholipid metabolism in first-episode, drug-naive schizophrenics. A pilot study of the dorsal prefrontal cortex by in vivo phosphorus 31 nuclear magnetic resonance spectroscopy.

Authors:  J W Pettegrew; M S Keshavan; K Panchalingam; S Strychor; D B Kaplan; M G Tretta; M Allen
Journal:  Arch Gen Psychiatry       Date:  1991-06

Review 2.  Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited.

Authors:  M S Keshavan; S Anderson; J W Pettegrew
Journal:  J Psychiatr Res       Date:  1994 May-Jun       Impact factor: 4.791

3.  Maternal complement C1q and increased odds for psychosis in adult offspring.

Authors:  Emily G Severance; Kristin L Gressitt; Stephen L Buka; Tyrone D Cannon; Robert H Yolken
Journal:  Schizophr Res       Date:  2014-09-04       Impact factor: 4.939

4.  Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning.

Authors:  Carl M Sellgren; Jessica Gracias; Bradley Watmuff; Jonathan D Biag; Jessica M Thanos; Paul B Whittredge; Ting Fu; Kathleen Worringer; Hannah E Brown; Jennifer Wang; Ajamete Kaykas; Rakesh Karmacharya; Carleton P Goold; Steven D Sheridan; Roy H Perlis
Journal:  Nat Neurosci       Date:  2019-02-04       Impact factor: 24.884

Review 5.  The complement system.

Authors:  J Vidya Sarma; Peter A Ward
Journal:  Cell Tissue Res       Date:  2010-09-14       Impact factor: 5.249

6.  Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.

Authors:  Konasale M Prasad; Kodavali V Chowdari; Leonardo A D'Aiuto; Satish Iyengar; Jeffrey A Stanley; Vishwajit L Nimgaonkar
Journal:  Transl Psychiatry       Date:  2018-07-19       Impact factor: 6.222

7.  Schizophrenia risk from complex variation of complement component 4.

Authors:  Aswin Sekar; Allison R Bialas; Heather de Rivera; Avery Davis; Timothy R Hammond; Nolan Kamitaki; Katherine Tooley; Jessy Presumey; Matthew Baum; Vanessa Van Doren; Giulio Genovese; Samuel A Rose; Robert E Handsaker; Mark J Daly; Michael C Carroll; Beth Stevens; Steven A McCarroll
Journal:  Nature       Date:  2016-01-27       Impact factor: 49.962
  8 in total
  6 in total

Review 1.  Brick by Brick: Building a Transdiagnostic Understanding of Inflammation in Psychiatry.

Authors:  David S Thylur; David R Goldsmith
Journal:  Harv Rev Psychiatry       Date:  2022 Jan-Feb 01       Impact factor: 3.732

Review 2.  Astrocyte Bioenergetics and Major Psychiatric Disorders.

Authors:  Ivan V Maly; Michael J Morales; Mikhail V Pletnikov
Journal:  Adv Neurobiol       Date:  2021

3.  Gray-Matter Morphometry of Internalizing-Symptom Dimensions During Adolescence.

Authors:  Harry R Smolker; Hannah R Snyder; Benjamin L Hankin; Marie T Banich
Journal:  Clin Psychol Sci       Date:  2022-03-15

Review 4.  Glutamate and microglia activation as a driver of dendritic apoptosis: a core pathophysiological mechanism to understand schizophrenia.

Authors:  Eduard Parellada; Patricia Gassó
Journal:  Transl Psychiatry       Date:  2021-05-06       Impact factor: 6.222

5.  Investigating the Relationship between White Matter Connectivity and Motivational Circuits in Subjects with Deficit Schizophrenia: A Diffusion Tensor Imaging (DTI) Study.

Authors:  Giulia M Giordano; Pasquale Pezzella; Mario Quarantelli; Paola Bucci; Anna Prinster; Andrea Soricelli; Andrea Perrottelli; Luigi Giuliani; Michele Fabrazzo; Silvana Galderisi
Journal:  J Clin Med       Date:  2021-12-23       Impact factor: 4.241

Review 6.  Imaging Synaptic Density: The Next Holy Grail of Neuroscience?

Authors:  Maria Elisa Serrano; Eugene Kim; Marija M Petrinovic; Federico Turkheimer; Diana Cash
Journal:  Front Neurosci       Date:  2022-03-25       Impact factor: 4.677
  6 in total

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