Literature DB >> 3191991

S-100b protein regulates the activity of skeletal muscle adenylate cyclase in vitro.

G Fanò1, S Fulle, G Della Torre, I Giambanco, M C Aisa, R Donato, P Calissano.   

Abstract

We have investigated the effect of the b isoform of S-100 proteins on adenylate cyclase activity of rat skeletal muscle. S-100b inhibits the adenylate cyclase activity in the presence of Mg2+ (5.0-50 mM), while it activates the same enzyme in the presence of Ca2+ (0.1-1.0 mM) dose-dependently in both cases. S-100b counteracts the stimulatory effect of NaF on adenylate cyclase in the presence of Mg2+ and the inhibitory effect of RMI 12330 A in the presence of Ca2+.

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Year:  1988        PMID： 3191991     DOI： 10.1016/0014-5793(88)80363-6

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Age-dependent expression of S100beta in the brain of mice.

Authors:  Prashant K Modi; M S Kanungo
Journal:  Cell Mol Neurobiol       Date:  2010-01-23       Impact factor: 5.046

2.  Antiserum against S-100 protein prevents long term potentiation through a cAMP-related mechanism.

Authors:  R Rebaudo; R Melani; M Balestrino; A Cupello; K Haglid; H Hydèn
Journal:  Neurochem Res       Date:  2000-04       Impact factor: 3.996

3.  Enhancement of S-100 beta protein in blood of patients with Down's syndrome.

Authors:  K Kato; F Suzuki; N Kurobe; K Okajima; N Ogasawara; M Nagaya; T Yamanaka
Journal:  J Mol Neurosci       Date:  1990       Impact factor: 3.444

4.  Elevated concentrations of the beta-subunit of S100 protein in renal cell tumors in rats.

Authors:  M Takashi; T Sakata; Y Nakano; Y Yamada; K Miyake; K Kato
Journal:  Urol Res       Date:  1994
  4 in total

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