Literature DB >> 31918861

Silencers, Enhancers, and the Multifunctional Regulatory Genome.

Marc S Halfon1.   

Abstract

Negative regulation of gene expression by transcriptional silencers has been difficult to study due to limited defined examples. A new study by Gisselbrecht et al. has dramatically increased the number of identified silencers and reveals that they are bifunctional regulatory sequences that also act as gene expression-promoting enhancers.
Copyright © 2019 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2020        PMID： 31918861     DOI： 10.1016/j.tig.2019.12.005

Source DB:  PubMed          Journal:  Trends Genet        ISSN： 0168-9525            Impact factor:   11.639


  7 in total

1.  Multiple sclerosis genetic and non-genetic factors interact through the transient transcriptome.

Authors:  Renato Umeton; Gianmarco Bellucci; Rachele Bigi; Silvia Romano; Maria Chiara Buscarinu; Roberta Reniè; Virginia Rinaldi; Raffaella Pizzolato Umeton; Emanuele Morena; Carmela Romano; Rosella Mechelli; Marco Salvetti; Giovanni Ristori
Journal:  Sci Rep       Date:  2022-05-09       Impact factor: 4.996

Review 2.  The Self-Organizing Genome: Principles of Genome Architecture and Function.

Authors:  Tom Misteli
Journal:  Cell       Date:  2020-09-24       Impact factor: 41.582

Review 3.  Common Themes and Future Challenges in Understanding Gene Regulatory Network Evolution.

Authors:  Isabella Schember; Marc S Halfon
Journal:  Cells       Date:  2022-02-01       Impact factor: 6.600

Review 4.  Mouse genomic and cellular annotations.

Authors:  Helen Long; Richard Reeves; Michelle M Simon
Journal:  Mamm Genome       Date:  2022-02-05       Impact factor: 2.957

Review 5.  REDfly: An Integrated Knowledgebase for Insect Regulatory Genomics.

Authors:  Soile V E Keränen; Angel Villahoz-Baleta; Andrew E Bruno; Marc S Halfon
Journal:  Insects       Date:  2022-07-11       Impact factor: 3.139

6.  Regulatory regions in natural transposable element insertions drive interindividual differences in response to immune challenges in Drosophila.

Authors:  Anna Ullastres; Miriam Merenciano; Josefa González
Journal:  Genome Biol       Date:  2021-09-14       Impact factor: 13.583

7.  Enhancer-silencer transitions in the human genome.

Authors:  Di Huang; Ivan Ovcharenko
Journal:  Genome Res       Date:  2022-02-01       Impact factor: 9.438
  7 in total

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