Kathleen M McIntyre1, Eli Puterman2, Jennifer M Scodes3, Tse-Hwei Choo3, C Jean Choi3, Martina Pavlicova4, Richard P Sloan5. 1. Division of Behavioral Medicine, Department of Psychiatry, Columbia University Medical Center. 2. School of Kinesiology, University of British Columbia. 3. Mental Health Data Science, New York State Psychiatric Institute. 4. Department of Biostatistics, Mailman School of Public Health, Columbia University. 5. Department of Psychiatry, Columbia University Medical Center.
Abstract
OBJECTIVE: The antidepressant and anxiolytic effects of aerobic exercise are well known, but less is known about its effects on subclinical levels of trait negative affect in healthy but sedentary adults. In the present study, we test the effects of a 3-month randomized controlled trial of aerobic exercise training in young to midlife adults on trait measures of depression, anxiety, hostility, and anger. METHOD: One-hundred and 19 men (n = 56) and women (n = 63) aged 20-45 were randomized to 1 of 2 conditions: (a) 12 weeks of aerobic exercise after which they were asked to halt exercising and decondition for 4 weeks, or (b) a 16-week waitlist control group. Assessments of depression, anxiety, hostility and anger were completed at study entry, Week 12 and Week 16. RESULTS: At study entry, participants scored low on measures of depression, anxiety, hostility and anger. Analyses among the intent-to-treat and per protocol samples found significant treatment effects of aerobic training for hostility and depression, but not for anxiety and anger. Within-group analyses demonstrated that depression and hostility scores decreased in the exercise group over the course of the intervention, while remaining stable in the control group. These effects persisted for the exercise group at nonsignificant levels after 4 weeks of deconditioning. CONCLUSIONS:Aerobic exercise training has significant psychological effects even in sedentary yet euthymic adults, adding experimental data on the known benefits of exercise in this population. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
RCT Entities:
OBJECTIVE: The antidepressant and anxiolytic effects of aerobic exercise are well known, but less is known about its effects on subclinical levels of trait negative affect in healthy but sedentary adults. In the present study, we test the effects of a 3-month randomized controlled trial of aerobic exercise training in young to midlife adults on trait measures of depression, anxiety, hostility, and anger. METHOD: One-hundred and 19 men (n = 56) and women (n = 63) aged 20-45 were randomized to 1 of 2 conditions: (a) 12 weeks of aerobic exercise after which they were asked to halt exercising and decondition for 4 weeks, or (b) a 16-week waitlist control group. Assessments of depression, anxiety, hostility and anger were completed at study entry, Week 12 and Week 16. RESULTS: At study entry, participants scored low on measures of depression, anxiety, hostility and anger. Analyses among the intent-to-treat and per protocol samples found significant treatment effects of aerobic training for hostility and depression, but not for anxiety and anger. Within-group analyses demonstrated that depression and hostility scores decreased in the exercise group over the course of the intervention, while remaining stable in the control group. These effects persisted for the exercise group at nonsignificant levels after 4 weeks of deconditioning. CONCLUSIONS: Aerobic exercise training has significant psychological effects even in sedentary yet euthymic adults, adding experimental data on the known benefits of exercise in this population. (PsycINFO Database Record (c) 2020 APA, all rights reserved).
Authors: Sammi R Chekroud; Ralitza Gueorguieva; Amanda B Zheutlin; Martin Paulus; Harlan M Krumholz; John H Krystal; Adam M Chekroud Journal: Lancet Psychiatry Date: 2018-08-08 Impact factor: 27.083
Authors: Elizabeth Brondolo; Ricardo Rieppi; Stephanie A Erickson; Emilia Bagiella; Peter A Shapiro; Paula McKinley; Richard P Sloan Journal: Psychosom Med Date: 2003 Nov-Dec Impact factor: 4.312
Authors: Richard P Sloan; Peter A Shapiro; Paula S McKinley; Matthew Bartels; Daichi Shimbo; Vincenzo Lauriola; Wahida Karmally; Martina Pavlicova; C Jean Choi; Tse-Hwei Choo; Jennifer M Scodes; Pamela Flood; Kevin J Tracey Journal: J Am Heart Assoc Date: 2018-09-04 Impact factor: 5.501