Meghan McGee1,2, Sharon Unger1,3,4,5, Jill Hamilton1,3,6, Catherine S Birken1,3,7,8,9, Zdenka Pausova1,2,10, Leigh M Vanderloo8, Nicole Bando2, Deborah L O'Connor1,2,4. 1. Nutritional Sciences, University of Toronto, Toronto, Canada. 2. Translational Medicine, The Hospital for Sick Children, Toronto, Canada. 3. Paediatrics, University of Toronto, Toronto, Canada. 4. Paediatrics, Mount Sinai Hospital, Toronto, Canada. 5. Division of Neonatology, The Hospital for Sick Children, Toronto, Canada. 6. Division of Endocrinology, The Hospital for Sick Children, Toronto, Canada. 7. Division of Paediatric Medicine, The Hospital for Sick Children, Toronto, Canada. 8. Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada. 9. Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada. 10. Physiology, University of Toronto, Toronto, Canada.
Abstract
BACKGROUND: Few studies have investigated how lifestyle is associated with body composition in children born very low birth weight (VLBW, <1500 g), a population at increased risk of obesity and metabolic syndrome in later life. OBJECTIVES: Determine how time spent in physical activity, sedentary time, and sleep are associated with body composition in children born VLBW. METHODS: In this prospective cohort study of 5.5-year-old children born VLBW, height, weight, body composition (skinfolds, air displacement plethysmography), and 7 days of movement data (logbooks and accelerometers) were collected. RESULTS: Of 158 participants, 53% were male, and mean (SD) birth weight was 1013 (264) g. Only 52% achieved 60 minutes/day of moderate-to-vigorous physical activity, but 96% achieved sleep recommendations. Reallocating 30 minutes of sedentary time to light physical activity (LPA) was associated with 0.20 kg/m2 (95% CI, 0.02 to 0.37) greater fat-free mass index. An equivalent inverse association was found when reallocating LPA to sedentary time. No associations were found for other movement behaviours. CONCLUSIONS: Promoting LPA and reducing sedentary time may be an important strategy in reducing the elevated risk of obesity and metabolic syndrome amongst those born VLBW by supporting lean mass accretion. Funded by CIHR (FHG 129919) and SickKids Restracomp.
BACKGROUND: Few studies have investigated how lifestyle is associated with body composition in childrenborn very low birth weight (VLBW, <1500 g), a population at increased risk of obesity and metabolic syndrome in later life. OBJECTIVES: Determine how time spent in physical activity, sedentary time, and sleep are associated with body composition in childrenborn VLBW. METHODS: In this prospective cohort study of 5.5-year-old childrenborn VLBW, height, weight, body composition (skinfolds, air displacement plethysmography), and 7 days of movement data (logbooks and accelerometers) were collected. RESULTS: Of 158 participants, 53% were male, and mean (SD) birth weight was 1013 (264) g. Only 52% achieved 60 minutes/day of moderate-to-vigorous physical activity, but 96% achieved sleep recommendations. Reallocating 30 minutes of sedentary time to light physical activity (LPA) was associated with 0.20 kg/m2 (95% CI, 0.02 to 0.37) greater fat-free mass index. An equivalent inverse association was found when reallocating LPA to sedentary time. No associations were found for other movement behaviours. CONCLUSIONS: Promoting LPA and reducing sedentary time may be an important strategy in reducing the elevated risk of obesity and metabolic syndrome amongst those born VLBW by supporting lean mass accretion. Funded by CIHR (FHG 129919) and SickKids Restracomp.
Authors: Klaas R Westerterp; Yosuke Yamada; Hiroyuki Sagayama; Philip N Ainslie; Lene F Andersen; Liam J Anderson; Lenore Arab; Issaad Baddou; Kweku Bedu-Addo; Ellen E Blaak; Stephane Blanc; Alberto G Bonomi; Carlijn V C Bouten; Pascal Bovet; Maciej S Buchowski; Nancy F Butte; Stefan G J A Camps; Graeme L Close; Jamie A Cooper; Sai K Das; Richard Cooper; Lara R Dugas; Ulf Ekelund; Sonja Entringer; Terrence Forrester; Barry W Fudge; Annelies H Goris; Michael Gurven; Catherine Hambly; Asmaa El Hamdouchi; Marije B Hoos; Sumei Hu; Noorjehan Joonas; Annemiek M Joosen; Peter Katzmarzyk; Kitty P Kempen; Misaka Kimura; William E Kraus; Robert F Kushner; Estelle V Lambert; William R Leonard; Nader Lessan; Corby K Martin; Anine C Medin; Erwin P Meijer; James C Morehen; James P Morton; Marian L Neuhouser; Theresa A Nicklas; Robert M Ojiambo; Kirsi H Pietiläinen; Yannis P Pitsiladis; Jacob Plange-Rhule; Guy Plasqui; Ross L Prentice; Roberto A Rabinovich; Susan B Racette; David A Raichlen; Eric Ravussin; Rebecca M Reynolds; Susan B Roberts; Albertine J Schuit; Anders M Sjödin; Eric Stice; Samuel S Urlacher; Giulio Valenti; Ludo M Van Etten; Edgar A Van Mil; Jonathan C K Wells; George Wilson; Brian M Wood; Jack Yanovski; Tsukasa Yoshida; Xueying Zhang; Alexia J Murphy-Alford; Cornelia U Loechl; Amy H Luke; Herman Pontzer; Jennifer Rood; Dale A Schoeller; William W Wong; John R Speakman Journal: Am J Clin Nutr Date: 2021-11-08 Impact factor: 7.045